Development of musculature - COle

Question 1

paraxial meso gives rise to

Answer 1

axial skeleton and skeletal muscle

Question 2

intermediate meso gives rise t o

Answer 2

urogenital system

Question 3

lateral plate meso gives rise to

Answer 3

CT and skeleton of limbs and smooth muscle and CT of viscera and blood vessels.
does not give rise to skeletal muscle

Question 4

protein that accumulates in presomatic meso destned to form next somite and then decreases as somite is established
activates other segment-patterning genes that establish the somite

Answer 4

NOTCH

Question 5

expression of which TF forms a gradient to control somatogenesis and activity of nothc pathway?

Answer 5

Retinoic acid cranially

FGF8 & WNT3a caudally

Question 6

3 parts that somite divides into?

Answer 6

scelerotome
dermatome
myotome

Question 7

resegmentation only takes place in the?

Answer 7

scelrotome

Question 8

any longitudinal axis is usually determined by thse genes

Answer 8

HOX

Question 9

expressed by scelerotome cells to initiate cartilage adn bone forming cascade

Answer 9

PAX1

Question 10

crucial for epaxial muscle formation - final TF

Answer 10

MYF5

Question 11

final TF for hypaxial muscle formation

Answer 11

MYOD

Question 12

cause expression of MYOD by dorsolateral somite

Answer 12

WNT from epidermis

BMP4 from lateral plate mesoderm

Question 13

crucial to formation of dermis by mid portion of somite

secreted by dorsal neural tube

Answer 13

NT-3

Question 14

sensory/ motor or BOTH

for roots, rami and nerves

Answer 14

spinal nerve has BOTH motor and sensory
rami have BOTH motor and sensory
roots have EITHER motor OR sensory

Question 15

what is the giveaway for caudal dysplasia?

Answer 15

type 1 diabetic mom