Cartilage - Cole Flashcards
cartilage growth stimulated by
somatotropin
thyroxin
testosterone
matrix formation & growth inhibited by
- cortisone
hydrocortisone
estradiol
hypovitaminosis A
retards growth, reduces width of epiphyseal plate
hypovitaminosis C
inhibits matrix synthesis, leads to deformation of epiphyseal plate —> scurvy
deformation = like deformation of the seas — sailiors - scurvy
vitamin D deficiency
chrondrocytes proliferate but matrix does not calcify properly —> rickets
extreme Ca+ loss
elastic cartilage
found in auricle auditory tube ear epiglottis laryngeal cartilages
fibrocartilage features
no perichondrium
chondrocytes in rows
abundant collagen I & II
ground substance has dermatan & chondroitin sulfate
ALWAYS has longintudinal oriented bundles and even short ones LINED UP
fibrocartilage found in
5
ligaments of articular surfaces symphysis pubis menisci labrum intervertebral discs
formation of new cartilage on surface of pre-existing cartilage (at periphery) called
appositional growth
cartilage made within cartilage mass itself isnide the lacunae called
interstitial growth (limited by AVASCULAR nature)
articular capsule made up of
fibrous capsule
synovial membrane
articular cartilage 6 features
hyaline cartilage reduces friciton between bones no nerves or blood vessels nourished by synovial fluid (capillries in synovial membrane) no perichondrium
synovial membrane repair mechanism?>
regeneration!
synovial membrane A cells
phagocytic
contain lyosomes, clear debris created by friciton of articular cartilages
Synovial membrane B cells
produce synovial fluid (plasma filtrate)
fluid contains hyaluronic acid to increase viscosity
lubricin -lubricates cartilage to reduce friciton
