Development Of Great vessels Flashcards
Paired dorsal artae
Connected to heart thru aortic arches, supply yolk sac
Fuse to become descending aorta
Aortic sac
Rostral most part of truncus arteriosus
Has paired aortic arches
Paired intersegmental arteries (branch of aorta)
Grow btwn somites to supply blood to body wall
Form: posterior intercostal aa., lumbar aa., subclavian aa., common iliac aa.
What forms subclavian aa.?
7th intersegmental aa.
What forms common iliac aa.?
5th lumbar intersegmental aa.
Unpaired vitelline arteries (branch of aorta)
Supplies yolk sac derivatives
Form esophageal and bronchial aa.; celiac, superior, and inferior mesenteries aa.
Paired umbilical arteries (aorta)
Forms (proximal) internal iliac arteries, superior vesical a., and medial umbilical ligamen
Paired lateral splanchnic arteries (aorta)
Form renal, suprarenal, and gonadal arteries
Truncus arteriosus
Arterial trunk that originates from both ventricles that will develop into aorta and pulmonary trunk
What aortic arches are major contributors to definitive arteries
3,4,6
What aortic arches degenerate?
1,2,5
What does aortic arch 1 form part of
Maxillary artery
What does aortic arch 2 form part of
Stapedial artery
Proximal part of Arch 3
Common carotid artery
What forms de novo from common carotid and what does it supply?
External carotid aa., supplies structures external to skull
Distal part of arch 3
Forms part of internal carotid artery (w/ dorsal aorta)
Which dorsal aortae degenerate?
Between 3rd and 4th arch
Left aortic arch 4
Contributes to Arch of Aorta (w/ aortic sac and left dorsal aorta)
What combines to make Definitive Arch of Aorta?
Left 4th aortic arch, left dorsal aorta, aortic sac
Rt 4th aortic arch
Right subclavian artery (w/ rt dorsal aorta and rt 7th intersegmental artery)
What forms right subclavian artery?
Rt 4th aortic arch, rt dorsal aorta, rt 7th intersegmental artery
What forms left subclavian artery?
Lt 7th intersegmental artery
What forms pulmonary trunk?
Aortic arch 6 with truncus arteriosus
Proximal aortic arch 6
Left and right pulmonary arteries
Distal aortic arch 6
Degenerates on right
Left becomes ductus arteriosus
Ductus arteriosus
2nd bypass of pulmonary circulation that shunts blood from left pulmonary artery to arch of aorta (closes at 3 mo old)
Ligamentum arteriosum
Fibrotic cord connecting Left Pulmonary Artery to arch of aorta
Remnant of ductus arteriosus
What forms brachiocephalic trunk
Aortic sac
Caudal part of right dorsal aorta fate
Degenerates
Btwn right 7 intersegmental artery and fused rt/lt dorsal aorta
Intersegmental arteries become X postnatal
Posterior intercostal
Lumbar
Common Iliac Aa.
Vitelline arteries become X postnatal
Esophageal, bronchial, celiac,
Superior and inferior mesenteries
Lateral splanchnic arteries become X post natal?
Renal, suprarenal, gonadal
Umbilical arteries become what postnatal
Internal iliac artery
Superior vesical artery
Right and left vitelline veins become
Hepatic sinusoids
Anterior cardinal vein becomes
Internal jugular vein
Right vitelline vein becomes
Hepatic portal vein, superior and inferior mesenteries, splenic [hepatic portal system]
part of IVC
Right anterior and right common cardinal veins become
SVC
Left umbilical vein becomes
Ligamentum teres heparin
Ductus venosus becomes
Ligamentum venosum
Foramen ovale becomes
Fossa ovalis
Ductus arteriosus becomes
Ligamentum arteriosus
Rt recurrent laryngeal nerve
6th pharyngeal arch; hooks around right subclavian artery (4th aortic arch)
left recurrent laryngeal nerve
hooks around ligamentum arteriosum (6th aortic arch) and arch of aorta (4th aortic arch)
Coarctation of aorta
narrowing of the aorta sup/inf to entrance of ductus arteriosus
postductal coarctation
inferior to ligmentum arteriosum , causes formation of two collaterals to reach DA
postductal collaterals (2)
anterior intercostal branches (ITA0 and posterior intercostal arteries (AA)
Sup and inf. epigastric arteries
*RIB NOTCHING”`
preductal coarctation
superior to patent ductus arteriosus
patent ductus arteriosus
failure of closure of ductus arteriosus; results in AA to PA shunting
- Rubella and Premies*
- NSAIDS and Prostaglandin Inhibitors to Treat**
abnormal right subclavian artery
causes dysphagia due to constricted esophagus
forms from rt 7th intersegment A and persistence of distal rt. dorsal aorta
double aortic arch
two arches due to persistence of distal rt. aorta
forms ring around trachea/esophagus
right aortic arch
anterior/posterior to esophagus and trachea (post=prob)
persistence of right aorta, abnorm degen of distal left dorsal aorta
what do right and left vitelline veins drain?
primitive gut
Ductus venosus
venous bypass of liver, does L to R shunt from left umbilical vein to IVC
ligamentum venosum
postnatal remnant of ductus venosus
left umbilical vein
carries O2 to fetus;
enters liver and drains into hepatic sinusoids and IVC
anterior and posterior cardinal veins
drain cephalic and caudal parts of early embryo
which veins ultimately degenerate at least in part?
left vitelline vein, rt umbilical vein, left common cardinal vein, posterior cardinal veins
where do the cardinal veins empty
into common cardinal–> sinus venosus
Right and Left anterior cardinal veins become
IJV, left brachiocephalic vein
right anterior cardinal vein becomes
right brachiocephalic vein
right cardinal veins become
SVC
partial part of posterior cardinal vein becomes
segment of IVC, segment of common iliac veins
double superior vena cava
persistence of terminal lt anterior cardinal vein connection between left brachiocephalic vein and left common cardinal vein
left SVC
terminal right anterior cardinal vein degenerates instead of left
