Development Flashcards
How is the neural tube formed?
Notocord induces neurulation, lateral edges of neural plate elevate, folds fuse in the midline
When is the neural tube completely closed?
Day 28-32
How does the neural tube close?
From the centre outwards, forming an anterior and posterior neuropore
What causes Spina Bifida?
Defect in the closure of the caudal tube, most common in lumbosacral region
Define Myelomeningocele
The most severe form of spina bifida where the spinal cord is in the cyst
What is another complication of spina bifida?
Hydrocephalus
What causes Anencephaly?
Closure of the cranial end of the neural tube
How can a NT defect be diagnosed?
Raised maternal serum alpha - fetoprotein
When is the spinal cord the same length as the vertebral column?
3rd month
Which 2 vesicles form the forebrain?
Telencephalon and Diencephalon
Which vesicle forms the midbrain?
Mesencephalon
Which vesicles form the hindbrain?
Metencephalon and Myelencephalon
