Development 3 Flashcards
What is gastrulation?
embryonic cells differentiate into 3 layers
What is ectoderm?
outerlayer of cells
will become skin and nervous system (brain and spinal cord for CNS)
What is mesoderm?
middle layer of cells
will become skeleton, muscles, and reproductive structures
What is endoderm?
inner layer of cells
will become digestive and respiratory lining and endocrine glands
IB: How do neural tubes develop?
Neural tube of embryonic chordates is formed
by infolding of ectoderm followed by elongation
of the tube
Neural tube: hollow structure in which the brain and spinal cord forms
Dorsal nerve: developed by early on neurulation (first month of gestation (development of womb)
Area on dorsal surface becomes neural plate (basis for nervous system)
IB: How does neural development work?
Neurons are initially produced by differentiation in neural tube
Immature neurons migrate to a final location
An axon grows from each immature neuron in response to chemical stimuli
A developing neuron forms multiple synapses
Synapses that are not used do not persist
Neural pruning involves the loss of unused neurons
The plasticity of the nervous system allows it to change with experience.
What happens during the 1st trimester?
0-12 weeks from fertilization
zygote begins cell division as it moves down oviduct
becomes blastocyst and implants in uterus
development of body organs (heart beats by week 4, testosterone secretes by week 7 if Y chromosome present which develops testes)
sucking reflex
by week 8 all major structures evident
embyro is now a fetus
embyro is most sensitive due to rapid growth
sensitive to radiation and drugs (teratogens), maternal lifestyle, viral infection, radiation
What happens during the 2nd trimester?
weeks 13 -24
fetus grows rapidly to 30cm
quite active, hair begins to develop, cartilage turns to bone
What happens during the 3rd trimester?
weeks 25-38
rapid growth to 51cm
fetal activity decreases (less room to move)
fully mature (ready for birth)
IB: Sex determination in males
SRY gene in Y chromosome causes the embryonic gonads to develop testes and secrete testosterone
Gene carries DNA-binding protein called TDF (testis determining factor), which stimulates the expression of other genes that causes testis development