Desquamation

Question 1

the most common adverse drug reactions effect is a ____.

Answer 1

rash

Question 2

the most common drug eruption is a ____.

Answer 2

Maculopapular

Question 3

Both Urticaria and angioedema are type ____ reactons

Answer 3

1

Question 4

Drug Induced Urticaria presents as pruritic red ____ and transient. Complications may include ____ .

Answer 4

wheals
angiodema

Question 5

Drug Induced Urticaria is a ____ Dx. For Tx, discontinue drugs and give ____ (benedryl). If severe give ____ and ____

Answer 5

clinical
H1 Antihistamine
IV steriods
Epinhephrine

Question 6

on physical exam, fixed drug eruptions ____ in the same location due to subsequent exposure to ____. No lasting effects but will present as sharply demarcated dull red or ____ lesions.

Answer 6

re-occur
drugs
brown

Question 7

The Dx for fixed drug eruptions is ____ and Tx is simple, avoidance of ____.

Answer 7

Clinical
Drug

Question 8

Maculopapular drug eruptions makes up for ___% of drug eruptions.

Answer 8

90

Question 9

Maculopapular drug eruptions

on physical exam this will appear as ____ ,Erythematous, macules and papules. _____ and confluent. ±Fever an will be onset ~ ___ week after drug initiation

Answer 9

Blanching
Symmetric
1

Question 10

Maculopapular drug eruption Dx is _____. Tx includes D/C Drug unless necessary, and _____ for pruritus. if any inflammation give them _____ steroids.

Answer 10

clinical
Antihistamines
topical

Question 11

(DIHS) Drug induced hypersenstivity reaction

(DIHS) Drug induced hypersenstivity reaction can be caused by _____, Allopurinol, and Sulfonamides

Answer 11

Anticonvulsants

Question 12

(DIHS) Drug induced hypersenstivity reaction

On physcial exam, DIHS will present as a ______ involvement viral or flu-like prodrome. a ______ rash often on the face, hand or foor edema.

Answer 12

systemic
morbiliform

Question 13

(DIHS) Dx is ______. Tx is to immiedatelty d/c ______. Administer IV/ ______. Monitor ______ dysfunction with CBC and CMP

Answer 13

drug
glucocorticoids
organ

Question 14

Drug eruptions are usually caused by ______ side-effects

Answer 14

medications

Question 15

on physical exam, Drug eruption will present as a ______. Dx is clinixal, and Tx is dependent on the erruption

Note: watch for systemic involement

Answer 15

rash

Question 16

Erythema Multiforme is usally initated by an infection specifficaly ______

Answer 16

HSV 1 and 2

Question 17

Erythema Multiforme

On physical exam, it will present with sharply demarcated red or pink “______ “ lesions. with __ zones. Particularly apparent on the ______ surfaces of Hands and extensor surfaces.

Answer 17

Target

3

Dorsal

Question 18

for E.M Dx is ______. Tx is self-limited and you would give an antiviral for ______. speciffically ______ 400mg twicde per day. for any symptom relief ______ is an option or topical steroids.

Answer 18

Clinical
acyclovir
antihistamine

Question 19

With SJS/TEN the patient will present 4-28 days after drug intake, “flu-like” symptoms, malaise, headache, ______ borders and nikolsky sign ______.

Answer 19

Raised
Positive

Question 20

almost always SJS/TEN (95%) will be due to drugs. specifally ______ or NSAIDs in some cases.

Answer 20

Allopurinol

Question 21

SJS/TEN Tx involves withdrawing the specific ______ causing this. the patient will need extensive ______ . both will require admission at a _____/_____

Answer 21

Drug
supportive-care
ICU/burn unit

Question 22

Pityriasis Rosea will have two distinictive characterisitc. First the “ _____ patch” and the “______\_________ “ pattern.

Answer 22

Herald
Christmas Tree

Note: Herald patch can also be “large round oroval patch”

Question 23

Pityriasis Rosea

on physical exam, on lighter skin the lesion will appear ______ or \________ colored, on dark skin it will appear violet or ______\________ .

Answer 23

pink
salmon
red brown

Question 24

Dx for Pityriasis Rosea is _______. Tx is primarlly supportive through antihistamines and _______ steroids.

Answer 24

clinical
topical

Question 25

Pityriasis Rosea is usually caused by _______ and commonly seen in _______ adults.

Answer 25

HHV
Young

Question 26

With Psoriasis, the eitolgoy is unknown but half of pateints report _______ history of disease.

Answer 26

Family

Question 27

in Psoriasis, some devolp at sites of trauma the _______ phenomenon

Answer 27

Koebner’s

Question 28

Psoariasis can be presented by erythematous, sharply demarcated _______ and rounded _______ covered by silvery micaceous _______

Answer 28

papules
plaques
scale

Question 29

Plaque Psoriasis

to distinguish this type of psoriasis, plaque is usually _______ and is characterized by _______ sign

Answer 29

symmetric
Auspitz

Question 30

Tx for plaque psoriasis is Topical _______ or _______.

Answer 30

corticosteroids
emolliments

Note: BSA>30% , give Methotrexate

Question 31

Guttate Psoriasis will present with many small _______, scaling _______. this type of Psoriasis is often triggered by an _______ _______ infection

Answer 31

erythematous
papules
upper respitory

Question 32

Tx for Guttate psoriasis inlcudes _______ and Topical _______

Answer 32

Phototherapy
Glucorticosteroids

Question 33

Pustular Psoriasis will present with a _______ (several days).

Answer 33

Fever

Question 34

Pustular Psoriasis Tx includes oral _______ or DMARD first line _______

Answer 34

Retnoids (Acitretin)
Methotrexate

Question 35

Erythodermic Psoriasis on physical exam will show involvement of more than ___% of BSA. its also a worsening acute progession chronic _____ psoriasis.

Answer 35

75
plaque

Question 36

Erythodermic Psoriasis Tx would include retnoid, specifically _____.

Answer 36

Acitretin

Question 37

Inverse Psoriasis affects _______ regions.
may be _____ due to locations.

Answer 37

intertrigous
moist

Ex: groin, breast folds, Axilla

Question 38

Inverse Psoriasis TX is low potency topical ___________.

Answer 38

Glucorticosteroids

Question 39

Some complications that could arise from Psoriasis could be Psoriasis _______, _______ disease and _______

Answer 39

Arthritis
cardiovascular (CV)
Pschological