Dernière chance Flashcards

1
Q

Goblet cells are found where and secrete what?

A

At epithelium and secrete mucinogen

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2
Q

Small cell produces what to vasodilate?

A

Serotonin

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3
Q

Small cell produces what to vasoconstricts?

A

Epinephrine

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4
Q

Esophageal atresia is seen with polyhydramnios. True or false?

A

True

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5
Q

What is fistula?

A

Trachea merge with bronchus

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6
Q

Two characteristics of bronchopulmonary cyst?

A

Cyst near mediastinum

Prone to infection

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7
Q

What is Potter syndrome?

A

No kidneys, no amniotic fluid, hence, lung hypoplasia

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8
Q

Low lecithin-sphingomyelin ratio is a sign of what?

A

Lack of surfactant detected before birth

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9
Q

Lack of surfactant in a not yet born child can be correct by what?

A

By giving steroid to the mother

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10
Q

During formation of the bronchi, cartilage is not form. This leads to what, and what is the name of the disease?

A

Congenital Lobar Emphesyma:

Bronchi collapse during expiration and the gas trapped leads to hyperinflation (treatment to ressection of lobe)

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11
Q

What is congenital cystic adenomatoid malformation (CCAM)?

A

Parts of lung stopped developping during pseudoglandular period
There’s no communication between terminal bronchioles and alveolar capillaries
Often asymptomatic

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12
Q

What is the mutated gene in Charge syndrome?

A

CHD7

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13
Q

Characteristics of Charge syndrome?

A

Autosomal dominant
Airway disease
Polyhydramnios
One form of atresia

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14
Q

Characteristics of Pompe disease (glycogenosis 2)

A

Autosomal recessive
Prone to infection
Muscular disease
Requires enzyme replacement therapy

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15
Q

Variation of pressure/Resistance = ?

A

Flow

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16
Q

Diseases with low diffusion capacities?

A

Emphysema
Interstitial lung disease
Pulmonary vascular disease
Anemia

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17
Q

Diseases with high diffusion capacities?

A

Asthma

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18
Q

How to calculate pulmonary vascular resistance?

A

(Pulm. Art. rpessure - Pulm. Left atrium pressure)/2.6mmHg

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19
Q

How to calculate systemic vascular resistance?

A

(Aorta pressure - Right atrium pressure)/19.6mmHg

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20
Q

Rate ratio?

A

Incidence rate in expoxed
_____________
Incidence rate in unexposed

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21
Q

Incidence rate?

A

Number of event/person-rate

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22
Q

Risk ratio?

A

Cumulative incidence in exposed
_________
Cumulative incidence in unexposed

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23
Q

Hazard ratio?

A

Time to event in exposed
___________
Time to event in unexposed

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24
Q

Attributable risk?

A

Incidence in exposed - Incidence in unexposed

25
Attributable fraction?
Attributable risk ___________ Incidence in exposed
26
What is cardiogenic pulmonary edema?
Heart attack leading to fluid not being pumped and going back to pulmonary circulation
27
3 types of edema?
Insterstitial pulmonary edema Alveolar pulmonary edema Cardiogenic pulmonary edema
28
What is interstitial pulmonary edema?
Fluid between alveolar epithelium and capillary endothelium
29
What is alveolar pulmonary edema?
When interstitial pulm. edema give rise to too much pressure | Rupture of alveolar epithelium and alveoli is flooded
30
What type of neurons do you find in the dorsal respiratory group?
Nucleus of the tractus solitatus (diaphragm)
31
What type of neurons do you find in the ventral respiratory group?
Retrotrapezoid nucleus (botzinger and pre-botzinger complexes)
32
Low O2 is sensed by what? In where?
By glomus cells, in the carotid body
33
High CO2 is sensed by what?
Retrotrapeizoid nucleus, at the botzinger complexes
34
High amount of eosinophils is a sign of what?
Asthma
35
What causes alpha-1 antitrypsin defficiency?
Panlobular emphysema
36
What is linked to a mutation of the CFTR channel?
Cystic fibrosis
37
Examples of non-parenchymal insterstitual lung disease?
Alveolar pulmonary disease | Sarcoidosis
38
Alveolar airspace edema and lymphocytes in septae are signs of which parenchymal interstitial lung disease?
Acute/Diffuse ILD
39
Granuloma non necrotizing and Kerley B lines are signs of what?
Sarcoidosis
40
Fibrosis Patchy Air bronchograms are signs of parenchymal interstitial lung disease?
Cryptogenic/Organizing
41
What is Pancoast syndrome, and what is it a sign of?
Pain in arm/hand because tumor at apex of lung press on brachial plexus
42
Horner's syndrome is a sign of what?
Of cancer!!
43
Lymphocytes infiltrate Cytamegalovirus are signs of which pattern pulmonary pneumonia?
Interstitial
44
Staphylococcus Aureus Empyema (pus) in pleural space are signs of which pattern pulmonary pneumonia?
Patchy
45
Outflow of liquid into the airspace is a sign of which pattern pulmonary pneumonia?
Diffuse: pneumococcus
46
``` Infection of airways No bronchograms Necrosis Empyema in pleural space are signs of which pneumonia ```
Staphylococcus
47
Edema at full lobe Can't spread to other lobes Diffuse pattern are signs of which pneumonia?
Streptococcus
48
Green sputum. Which pneumonia?
Pseudomonas
49
Which cancers show hypercalcemia?
All the non small cell cancers: Squamous Adenomacarcinoma Mesothelioma
50
Mucin production is a sign of which cancer?
Adenomacarcinoma
51
Cushing Present at hilum are signs of which cancer?
Small cell
52
Congenital disease Empyema: pus in the pleura Pneumothorax What is it?
Pulmonary sequestration
53
Mutation of FGFR3 may lead to what?
Thanatophoric dysplasia Achondroplasia (remember what are those?)
54
On airflow/lung volume tab restrictive disease shifts the curve how?
To the right, down
55
On airflow/lung volume tab obstructive disease shifts the curve how?
To the left, down
56
(2 x Tension)/radius =
Pressure
57
At FRC, which part of the lung fill more easily?
Bottom will inflate first
58
At RV, which part of the lung fill more easily?
Top will inflate first