Dernière chance Flashcards

1
Q

Goblet cells are found where and secrete what?

A

At epithelium and secrete mucinogen

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2
Q

Small cell produces what to vasodilate?

A

Serotonin

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3
Q

Small cell produces what to vasoconstricts?

A

Epinephrine

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4
Q

Esophageal atresia is seen with polyhydramnios. True or false?

A

True

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5
Q

What is fistula?

A

Trachea merge with bronchus

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6
Q

Two characteristics of bronchopulmonary cyst?

A

Cyst near mediastinum

Prone to infection

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7
Q

What is Potter syndrome?

A

No kidneys, no amniotic fluid, hence, lung hypoplasia

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8
Q

Low lecithin-sphingomyelin ratio is a sign of what?

A

Lack of surfactant detected before birth

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9
Q

Lack of surfactant in a not yet born child can be correct by what?

A

By giving steroid to the mother

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10
Q

During formation of the bronchi, cartilage is not form. This leads to what, and what is the name of the disease?

A

Congenital Lobar Emphesyma:

Bronchi collapse during expiration and the gas trapped leads to hyperinflation (treatment to ressection of lobe)

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11
Q

What is congenital cystic adenomatoid malformation (CCAM)?

A

Parts of lung stopped developping during pseudoglandular period
There’s no communication between terminal bronchioles and alveolar capillaries
Often asymptomatic

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12
Q

What is the mutated gene in Charge syndrome?

A

CHD7

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13
Q

Characteristics of Charge syndrome?

A

Autosomal dominant
Airway disease
Polyhydramnios
One form of atresia

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14
Q

Characteristics of Pompe disease (glycogenosis 2)

A

Autosomal recessive
Prone to infection
Muscular disease
Requires enzyme replacement therapy

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15
Q

Variation of pressure/Resistance = ?

A

Flow

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16
Q

Diseases with low diffusion capacities?

A

Emphysema
Interstitial lung disease
Pulmonary vascular disease
Anemia

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17
Q

Diseases with high diffusion capacities?

A

Asthma

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18
Q

How to calculate pulmonary vascular resistance?

A

(Pulm. Art. rpessure - Pulm. Left atrium pressure)/2.6mmHg

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19
Q

How to calculate systemic vascular resistance?

A

(Aorta pressure - Right atrium pressure)/19.6mmHg

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20
Q

Rate ratio?

A

Incidence rate in expoxed
_____________
Incidence rate in unexposed

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21
Q

Incidence rate?

A

Number of event/person-rate

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22
Q

Risk ratio?

A

Cumulative incidence in exposed
_________
Cumulative incidence in unexposed

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23
Q

Hazard ratio?

A

Time to event in exposed
___________
Time to event in unexposed

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24
Q

Attributable risk?

A

Incidence in exposed - Incidence in unexposed

25
Q

Attributable fraction?

A

Attributable risk
___________
Incidence in exposed

26
Q

What is cardiogenic pulmonary edema?

A

Heart attack leading to fluid not being pumped and going back to pulmonary circulation

27
Q

3 types of edema?

A

Insterstitial pulmonary edema
Alveolar pulmonary edema
Cardiogenic pulmonary edema

28
Q

What is interstitial pulmonary edema?

A

Fluid between alveolar epithelium and capillary endothelium

29
Q

What is alveolar pulmonary edema?

A

When interstitial pulm. edema give rise to too much pressure

Rupture of alveolar epithelium and alveoli is flooded

30
Q

What type of neurons do you find in the dorsal respiratory group?

A

Nucleus of the tractus solitatus (diaphragm)

31
Q

What type of neurons do you find in the ventral respiratory group?

A

Retrotrapezoid nucleus (botzinger and pre-botzinger complexes)

32
Q

Low O2 is sensed by what? In where?

A

By glomus cells, in the carotid body

33
Q

High CO2 is sensed by what?

A

Retrotrapeizoid nucleus, at the botzinger complexes

34
Q

High amount of eosinophils is a sign of what?

A

Asthma

35
Q

What causes alpha-1 antitrypsin defficiency?

A

Panlobular emphysema

36
Q

What is linked to a mutation of the CFTR channel?

A

Cystic fibrosis

37
Q

Examples of non-parenchymal insterstitual lung disease?

A

Alveolar pulmonary disease

Sarcoidosis

38
Q

Alveolar airspace edema and lymphocytes in septae are signs of which parenchymal interstitial lung disease?

A

Acute/Diffuse ILD

39
Q

Granuloma non necrotizing and Kerley B lines are signs of what?

A

Sarcoidosis

40
Q

Fibrosis
Patchy
Air bronchograms
are signs of parenchymal interstitial lung disease?

A

Cryptogenic/Organizing

41
Q

What is Pancoast syndrome, and what is it a sign of?

A

Pain in arm/hand because tumor at apex of lung press on brachial plexus

42
Q

Horner’s syndrome is a sign of what?

A

Of cancer!!

43
Q

Lymphocytes infiltrate
Cytamegalovirus
are signs of which pattern pulmonary pneumonia?

A

Interstitial

44
Q

Staphylococcus Aureus
Empyema (pus) in pleural space
are signs of which pattern pulmonary pneumonia?

A

Patchy

45
Q

Outflow of liquid into the airspace is a sign of which pattern pulmonary pneumonia?

A

Diffuse: pneumococcus

46
Q
Infection of airways
No bronchograms
Necrosis
Empyema in pleural space
are signs of which pneumonia
A

Staphylococcus

47
Q

Edema at full lobe
Can’t spread to other lobes
Diffuse pattern
are signs of which pneumonia?

A

Streptococcus

48
Q

Green sputum. Which pneumonia?

A

Pseudomonas

49
Q

Which cancers show hypercalcemia?

A

All the non small cell cancers:
Squamous
Adenomacarcinoma
Mesothelioma

50
Q

Mucin production is a sign of which cancer?

A

Adenomacarcinoma

51
Q

Cushing
Present at hilum
are signs of which cancer?

A

Small cell

52
Q

Congenital disease
Empyema: pus in the pleura
Pneumothorax

What is it?

A

Pulmonary sequestration

53
Q

Mutation of FGFR3 may lead to what?

A

Thanatophoric dysplasia
Achondroplasia
(remember what are those?)

54
Q

On airflow/lung volume tab restrictive disease shifts the curve how?

A

To the right, down

55
Q

On airflow/lung volume tab obstructive disease shifts the curve how?

A

To the left, down

56
Q

(2 x Tension)/radius =

A

Pressure

57
Q

At FRC, which part of the lung fill more easily?

A

Bottom will inflate first

58
Q

At RV, which part of the lung fill more easily?

A

Top will inflate first