Dermatopathology Flashcards
Merkels cells
Function as mechanoreceptors
Melanocytes
Pigment synthesizing cells
SUpply keratinocytes with melanin
Langerhans cells
Scattered in suprabasal layer of epidermis
Immunogenic cells that recognize foreign antigens.
Bind antigen, send it to node
Dermis
Mostly composed of collagen
Immune cells, nerves, vessels
Eccrine (merocrine) glands
Sweat glands
Located over entire body
Open directly to skin surface
Apocrine glands
Sweat glands
Open through a HAIR FOLLICLE
Less numerous
Secrete more of an oily substance
Sebaceous Glands
Secrete sebum, an oily substance
Lubricates hair and skin
Eponychium
Nail bed
Nail plate lies on top
Primary lesions
Arise from previously normal skin
Secondary lesion
Created by another process such as scratching or infxn
Circumscribed flat lesion <1cm
Freckle
Macule
Circumscribed flat lesion >1 cm
Patch
Elevated solid lesion with variable color <.5 cm
Papule
Raised, flat-topped superficial lesion where diameter is greater than the thickness. >.5 cm
Plaque
Often the product of a coalescence of papules
Elevated lesion with a rounded surface.
.5 - 1-2 cm
Nodule
Generally deeper and firmer than papule