Dermatology and Rheumatology Flashcards
Biopsy finding in pemphigoid
IgG/C3 deposition at the dermo-epidermal junction
Management of Still’s Disease
NSAIDs in first instance
Steroids
Anakinra/MTX if not improving with steroids
Mononeuritis multiplex
ANCA +VE
Microscopic Polyangiitis
Felty’s syndrome
RA, splenomegaly, neutropaenia = classic triad
May also see recurrent infections, lymphadenopathy, leukopaenia, ulcers and episcleritis
Factors associated with guttate psoriasis
Beta blocker
Lithium
Streptococcus
Viral infection
Lichen planus
- precipitant
- feature
Can be precipitated by B blockers
Can exhibit Koeber’s phenomenon
SCC management
- immunosuppressed
Surgery + retinoid
e.g. acitretin - reduces risk of further SCC
DIP + morning stiffness
Psoriatic arthritis
Monitoring of MTX
Every 1-2 weeks until they are stable on dose
Then every 2-3 months
HCQ in Lupus
Avoid in severe renal impairment
e.g. acute lupus
= use IV cyclophosphamide + steroids
Treatment of PBC
Ursodeoxycholic acid = reduces progression
Cholestyramine = reduces itch by sequestering bile acids
Erythematous reaction during vancomycin
Red Man Syndrome
= related to rate of vancomycin: not an allergic reaction
Erythema associated with sunlight, sparing face
Polymorphic light eruption
Eruption of seborrheic keratoses
- consideration
= Leser-trelat sign
Need to consider malignancy - associated with GI cancer
Diagnosis of primary Sjogren’s syndrome
Salivary gland biopsy
Diagnosis of polyarteritis nodosa
Renal angiogram
Management of GCA where steroids cannot be weaned
Methotrexate
Management of Still’s Disease
NSAIDs
- can use steroids if nil response or evidence of organ dysfunction
Biochemical marker in Paget’s Disease
C-telopeptide
