Dermatology Flashcards
What is the most common bacterial skin commensal?
What is the most common fungal skin commensal?
Staphylococcus pseudintermedius
Malassezia
What is an example of a primary skin pathogen?
Dermatophytes
What is pyotraumatic dermatitis caused by?
What is the treatment?
Self-trauma due to underlying trigger: allergy, pruritus, pain
Clip, clean, topical antiseptics/antimicrobials, steroids
What is the common locations for Bacterial Overgrowth?
What is the differential diagnosis
Ventral trunk and interdigital spaces
Malassezia dermatitis
What may you see on cytological examination of deep pyoderma that you wouldn’t see with superficial or surface pyoderma?
Erythrocytes
Macrophages
Is surface pyoderma pyogenic? What WOULDN’T you see on cytological exmination?
Not pyogenic
Wouldn’t see neutrophils
What is the best way to sample a deep pyodermal infection for culture?
Fresh tissue sample (biopsy punch)
What is MRSP?
What is it resistant to?
Meticillin Resistant S. pseudintermedius
Beta-lactams (penicillins) + fluoroquinolones
Can be multidrug resistant or panresistant
What are risk factors for MRSP?
Hospital admission
Multiple vet visits
Previous (especially broad spectrum) systemic antimicrobials
How long should you treat deep pyoderma with systemic antimicrobials?
What do you do if progress stops with treatment?
Treat past clinical, cytological and palpable cure (4-12 weeks)
Repeat culture
What are the 4 mechanisms of pathogenesis of Canine Atopic Dermatitis?
- Cutaneous inflammation and pruritus
- Defective skin barrier function
- Microbial colonisation
- Other flare factors
What is the age range at which dogs develop signs of cAD?
What about FIAD?
< 3 years old (up to 6 years)
FIAD < 1 year old
How many of Favrot’s criteria is needed for a diagnosis of cAD with 85% sensitivity and 79% specificity
5/7 criteria
Name a pruritic cytokine involved in cAD
Interleukin-31 (IL-31)
Name a pruritic cytokine involved in cAD
What specific therapy targets this?
Interleukin-31 (IL-31)
Lokivetmab (Cytopoint) injections
Anti-canine IL-31 monoclonal antibody
When should oclacitinib (Apoquel) NOT be used?
In dogs < 12 months