dermatology Flashcards
common location SCC
lower lip, head and neck, external ear, forehead, scalp
in melanoma, when does vertical growth phase occur
after radial growth
Basal cell typically located
upper lip (rarely mets)
drugs that can cause psoriasis
beta blockers, lithium, NSAIDs, ethanol
Bullous pemphigoid pathophysiology
IgG Abs against dermal-epidermal basement membrane proteins (hemidesmosomes) -> leads to supepidermal bullae
Bullous pemphigoid and Pempigus vulgaris imaging
- immunofluorescence shows linear deposits of IgG and C3
- in base memb in BP (deep)
- in epidermis in PV (superficial)
Bullous pemphigoid negative or positive Nikolsky’s sign?
negative
Pempigus vulgaris typical age and culture
40-60 (and higher prevalence in jewish, mediterranean, asian people)
bullous pemphigoid typical age
60-80
Pempigus vulgaris Nikolsky’s sign
sliding or rubbing pressure on skin causes suparation of epidermis
most common causes of erythema multiforme
mycoplasma pneumonia, HSV (rarely drugs - sulfonamides, penicillin, phenytoin)
pityriasis rosea is typically from
Human Herpesvirus 7
pityriasis rosea begins as a what, which develops into a what?
herald patch –> christmas tree distribution on trunk
a furuncle is aka
boil
what is a furuncle
deep folliculitis (infx of hair follicle) usually from staph a