Dermatology

Question 1

“Stuck-on” appearance

Answer 1

Basal cell papilloma (seborhaeic keratoses)

Question 2

Picket fence pearly border

Answer 2

Basal cell carcinoma

Question 3

Common association with Dermatitis Herpetiforme

Answer 3

Coeliac Disease

Question 4

Common diseases with Erythema Nodosum as dermatological manifestation

Answer 4

Sarcoid, TB, IBD commonly

Question 5

Honey coloured crust + common causative organism

Answer 5

Impetigo (Commonly Staph Aureus or Group A Strep)

Question 6

Cafe au lait spots

Answer 6

Neurofibromatosis Type 1 or 2 (usually >5 indicates genetic disease, most people have 1 or 2)

Question 7

Small, umbilicated, translucent papules that look fluid-filled but are solid

Answer 7

Molluscum Contagiosum (caused by molluscum contagiosum virus) - Self-limiting

Question 8

Monomorphic punched-out lesion in children + fever

Answer 8

Eczema Herpeticum

Question 9

Most important gene involved in atopic eczema

Answer 9

Filaggrin

Question 10

Pemphigus Vulgaris vs Bullous Pemphigoid

Answer 10

Pemphigus: Superficial blisters, Younger patients, intraepidermal acantholysis (Tzanck smear acantholysis), Flaccid blister and rupture easily, Antibody against Desmoglein 3 (Desmosomes), Net-like IgG, Patients die without treatment, Nikowsky +ve, Mucosal involvement (inc oral lesions) common

Pemphigoid: Deep Subepidermal blisters, Older patients, no intraepidermal acantholysis (even upon Tzanck smear), Blisters are tense and firm, Antibody against hemidesmosomes, Linear IgG, Good prognosis with Corticosteroids or DMARDS, Nikowsky -ve, Mucosal involvement rare (oral lesions absent)

Question 11

Ash Leaf Spots/Shagreen patches

Answer 11

Tuberous Sclerosis

Question 12

Target lesion

Answer 12

erythema multiforme

Question 13

Erythematous Bullseye lesion

Answer 13

Lyme disease