Dermatology

Question 1

stem cell site?

Answer 1

Stratum Basale

Question 2

desmosomes?

Answer 2

Stratum Spinosum

Question 3

keratin?

Answer 3

Stratum Corneum

Question 4

Freckle, labial macule are due to increased?

Answer 4

of melanosomes

Question 5

Psoriasis is due to increased?

Answer 5

Hyperkeratosis and Parakeratosis

Question 6

Hyperkeratosis?

Answer 6

Increased thickness of stratum corneum

Question 7

Parakeratosis

Answer 7

Hyperkeratosis with retention of nuclei in

stratum corneum

Question 8

Eczematous dermatitis that has skin erythema, vesicles and oozing over the upper eye lids?

Answer 8

Spongiosis

Question 9

Spongiosis?

Answer 9

Epidermal accumulation of edematous fluid in intercellular spaces

Question 10

Pemphigus vulgaris?

Answer 10

Acantholysis

Question 11

Acantholysis?

Answer 11

Separation of epidermal cells

Question 12

Acanthosis nigricans?

Answer 12

Epidermal Hyperplasia (increased spinosum)

Question 13

Normal melanocyte number with decreased 􏰂melanin production?

Answer 13

Albinism

Question 14

Albinism MOA?

Answer 14

defective tyrosine transport OR failure of neural crest cell migration

Question 15

Albinism leads to increased risk of?

Answer 15

Skin Cancer

Question 16

Hyperpigmentation associated with pregnancy ?

Answer 16

Melasma (chloasma)

Question 17

Patchy areas of complete depigmentation?

Answer 17

Vitiligo

Question 18

Vitiligo MOA?

Answer 18

Autoimmune destruction of melanocytes

Question 19

P.Acnes MOA?

Answer 19

P. Acnes=>lipases=>inflammation

Question 20

Allergic contact dermatitis HSR?

Answer 20

Type IV hypersensitivity reaction that follows exposure to allergen

Question 21

Papules and plaques with silvery scaling H , especially on knees and elbows?

Answer 21

Psoriasis

Question 22

pin point bleeding spots from exposure of dermalpapillae when scales are scraped off

Answer 22

Auspitz sign

Question 23

nail pitting?

Answer 23

Psoriasis

Question 24

Psoriasis with parakeratotic scaling is with?

Answer 24

Increased 􏰀stratum spinosum,􏰂 decreased stratum granulosum

Question 25

Epithelial proliferation with keratin-filled cysts that looks it can peeled off

Answer 25

Seborrheic keratosis

Question 26

Leser-Trélat sign?

Answer 26

sudden appearance of multiple seborrheic keratoses, indicating an underlying malignancy (e.g., GI, lymphoid).

Question 27

HPV. Soft, tan-colored, cauliflower-like papules ?

Answer 27

Verrucae

Question 28

Pruritic eruption, commonly on skin flexures like antecubital fossae; Commonly associated with eating certain foods

Answer 28

Atopic dermatitis (eczema)

Question 29

Atopic dermatitis (eczema) HSR?

Answer 29

Type 1 HSR

Question 30

Highly contagious. Honey- colored crusting? MC?

Answer 30

Impetigo; S. aureus.

Question 31

Acute, painful, spreading infection of deeper dermis and subcutaneous tissues? MC?

Answer 31

Cellulitis=>S. pyogenes or S. aureus

Question 32

Deeper tissue injury, usually from anaerobic bacteria?

Answer 32

Necrotizing fasciitis

Question 33

Staphylococcal scalded skin syndrome is due S. Aureus toxins?

Answer 33

Exfoliative toxin A and B

Question 34

Umbilicated papules caused by a poxvirus in children, it may be sexually transmitted in adults?

Answer 34

Molluscum contagiosum

Question 35

white, painless plaques on tongue that cannot be scraped off?

Answer 35

Hairy leukoplakia

Question 36

Hairy leukoplakia is due to?

Answer 36

EBV

Question 37

Hairy leukoplakia is usually on what side of the tongue?

Answer 37

Lateral

Question 38

IgG antibody against desmoglein (component of desmosomes) in Stratum spinosum?

Answer 38

Pemphigus vulgaris

Question 39

IF in Pemphigus Vulgaris?

Answer 39

antibodies around epidermal cells in a reticular (net-like) pattern

Question 40

Separation of epidermis upon manual stroking of skin is seen in?

Answer 40

Pemphigus vulgaris | Nikolsky sign ⊕

Question 41

IgG antibody against hemidesmosomes (epidermal basement membrane)?

Answer 41

Bullous pemphigoid

Question 42

In Bullous Pemphigoid, Tense blisters containing eosinophils affect skin but spare

Answer 42

oral mucosa

Question 43

IF in Bullous Pemphigoid?

Answer 43

linear pattern at epidermal-dermal junction | Negative Nikolsky sign

Question 44

Dermatitis herpetiformis?

Answer 44

Associated with celiac disease.

Question 45

Erythema multiforme MC seen in?

Answer 45

HSV

Question 46

Epidermal hyperplasia causing symmetric, hyperpigmented thickening of skin

Answer 46

Acanthosis nigricans

Question 47

Acanthosis nigricans is associated with?

Answer 47

hyperinsulinemia (e.g., diabetes*, obesity, Cushing syndrome), visceral malignancy (e.g., gastric adenocarcinoma*)

Question 48

Premalignant lesions caused by sun exposure?

Answer 48

Actinic keratosis

Question 49

Actinic keratosis increases risk for?

Answer 49

squamous cell carcinoma

Question 50

Lichen Planus 6 P'S

Answer 50

Pruritic, Purple, Polygonal Planar Papules and Plaques are the 6 P’s of lichen Planus

Question 51

Lichen planus manifests as?

Answer 51

Mucosal involvement manifests as Wickham striae (reticular white lines)

Question 52

Lichen planus has what kind of appearance?

Answer 52

Sawtooth

Question 53

Lichen planus is associated with?

Answer 53

HCV

Question 54

atypical kertinocytes with hyperkeratosis and parakeratosis?

Answer 54

Actinic Keratosis

Question 55

HLA-C is seen in?

Answer 55

Psoriasis

Question 56

Psoriasis treatment?

Answer 56

UVA

Question 57

Why is vit. A a good treatment in Acne?

Answer 57

Decreases keratin products

Question 58

In Hives, you will see increased?

Answer 58

Dermal edema