Dermatological Disease In Systemic Disease

Question 1

What are dermatological diseases associated with DM

Answer 1

ØPsoriasis
ØVitiligo
ØLichen planus
ØHidradenitis suppurativa

Question 2

Skin manifestations caused by DM medications

Answer 2

Insulin:
local: lipodystrophy
Systemic :urticaria

Oral hypoglycemics: exanthematous eruptions

Question 3

Skin manifestations associated with cirrhosis

Answer 3

• Spider angiomas, telangiectasias
• Palmar erythema
• Dilated abdominal wall veins
• Terry’s nails (white nail bed)
• Sparse axillary, pubic and pectoral hair
• Gynecomastia
• Pruritus, Jaundice

Question 4

Skin manifestations associated with hepatitis B and C

Answer 4

• Small vessel vasculitis,
cryoglobulineamia, polyarteritis
nodosa, Livedo reticularis
• Urticaria, Pruritus (hep.B, hep.C)
• Lichen planus – particularly erosive oral
disease (hep.C) (hep.C> hep.B)
• Erythema multiforme (hep.B, hep

Question 5

Skin manifestations associated with hemochromatosis(bronze diabetes)

Answer 5

Generalized hyperpigmentation

Question 6

Most severe cutaneous manifestation of end stage kidney disease

Answer 6

Calciphylaxis

Question 7

Apple jelly appearnace in diascopy is pathognomonic of which disease

Answer 7

Sarcoidosis

Question 8

Most common non specific skin lesion in sarcoidosis

Answer 8

Erythema nodosum

Question 9

Löfgren syndrome cl/p

Answer 9

erythema nodosum, fever, arthralgias,
acute bilateral hilar adenopathy.

Question 10

lupus pernio” appears in which disease

Answer 10

Sarvoidosis

Question 11

What is the diascopy finding of erythema nodosum

Answer 11

Paniculitis

Question 12

Skin manifestations associated with DM

Answer 12

A. Metabolic:
• Acanthosis Nigricans
• Skin tags
• Eruptive xanthomas
• Scleroderma like changes
B. Vascular:
• Diabetic dermopathy
C. Diabetic foot syndrome
D. Necrobiotic/granulomatous
• Necrobiosis lipoidica
• Disseminated Granuloma annulare
E. Bullous:
• Bullous diabeticorum
F. Miscellaneous:
• Pruritus
• Xerosis
• Thick skin