Allergy And Hypersensitivity

Question 1

What is the characteristic lesion of urticaria

Answer 1

Wheals

Question 2

Urticaria is a (superficial / deep skin lesion)

Answer 2

Superficial

Question 3

The wheals of urticaria is chararised by

Answer 3

It comea and goes rapidly within 24 hrs

Question 4

Heriditary angioedema is caused by…

Answer 4

C1 esterase inhibitor
deficiency

Question 5

Treatment od allergic reactions

Answer 5

Allergen avoidance
• Antihistamines
• Corticosteroids
• Leukotriene receptor antagonists i.e. Montelukast
• Monoclonal antibodies omalizumab SC
• Desensitization (antigen specific monotherapy)

Question 6

Pathogenesis of Steven johnson syndrome / TEN.

Answer 6

Type IV hypersensitivity reaction

Question 7

Treatment of Steven johnson syndrome /TEN

Answer 7

IVIg, cyclosporine, Prednisolone, Biological agent
(etanercept).

Question 8

DD of Steven johnson syndrome /TEN

Answer 8

Staphylococcal scalded skin syndrome
• Other bullous disease of the skin

Question 9

The most common form of cutaneous drug
eruption

Answer 9

Exanthematous erup>ons

Question 10

Treatment of exanthematous drug eruptions

Answer 10

• Topical steroids
• Antihistamines
• Supportive treatment

Question 11

Prognosis of exanthematous drug eruptions

Answer 11

Good prognosis