Bullous Disorders Pathology Flashcards
Deep form of pemphigus is which disease
Pemphigus vulgaris
Superficial form of pemphigus is called
Pemphigus foliaceus
What is the difference between pemphigus vulgaris amd pemphigus foliaceus
In pemphigus folacieus, there is no oral affection
Layer at which there is desmosomal separation in pemphigus vulgaris
Suprabasal
Layer at which there is desmosomal separation in pemphigus folacieus
Sub corneal (ta7t el keratinous layer)
Immunufluorescence antibodyinvolved in pemphigus folacieus and vulgaris
IgG
Where do antibodies in pemphigus vulgaris and folacieus attach
Desmosomes
Where do antibodies in bullous pemphigoid attach?
Hemidesmosomes
Immunofluorescence in bullous pemphigoid
IgG and C3
Immunofluorescence in Dermatitis herpetiformis
Granular IgA deposits within the papillary dermis.
Most common cause of erythema multiform (Major)
Drugs
Most common cause of erythema multiform (minor)
Herpes simplex
Drug causing pemphigus folacieus
Penicillamines