Bullous Disorders Pathology Flashcards

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1
Q

Deep form of pemphigus is which disease

A

Pemphigus vulgaris

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2
Q

Superficial form of pemphigus is called

A

Pemphigus foliaceus

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3
Q

What is the difference between pemphigus vulgaris amd pemphigus foliaceus

A

In pemphigus folacieus, there is no oral affection

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4
Q

Layer at which there is desmosomal separation in pemphigus vulgaris

A

Suprabasal

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5
Q

Layer at which there is desmosomal separation in pemphigus folacieus

A

Sub corneal (ta7t el keratinous layer)

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6
Q

Immunufluorescence antibodyinvolved in pemphigus folacieus and vulgaris

A

IgG

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7
Q

Where do antibodies in pemphigus vulgaris and folacieus attach

A

Desmosomes

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8
Q

Where do antibodies in bullous pemphigoid attach?

A

Hemidesmosomes

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9
Q

Immunofluorescence in bullous pemphigoid

A

IgG and C3

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10
Q

Immunofluorescence in Dermatitis herpetiformis

A

Granular IgA deposits within the papillary dermis.

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11
Q

Most common cause of erythema multiform (Major)

A

Drugs

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12
Q

Most common cause of erythema multiform (minor)

A

Herpes simplex

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13
Q

Drug causing pemphigus folacieus

A

Penicillamines

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