Lichen Planus & pitryasis Rosea Flashcards
Etiology of lichen Planus
T cell-mediated autoimmune disorder
• Genetic predisposition
• Stress
• Injury to the skin( scratch or after surgery)
(koebnerisation)
• viral infection, such as hepatitis C
(LICHEN –LIVER )
• Drugs; Quinine,Gold,Hydroxychloroquine
&Captopril
Diagnosis of lichen Planus
clinical features
• Biopsy
• Direct immunofluorescent
staining of immunoglobulins at the base of the epidermis
• Hepatitis markers
Management of lichen Planus
Topical
. Potent topical. Steroids
. Topical calcineurine inhibitors
. Topical retinoids
. Intralesional steroid injections
Systemic
. Steroids
. Hydroxychloroquine
. Acitretin
. Phototherapy
.
Age group affected in pitryasis rosea
Children and young adults
Etiology of pitryasis rosea
Idiopathic
Trigger is upper respiratory tract infection
Cl/p of pitryasis rosea
Herald patch
2ary rash after days of herald patch (Tshirt distribution) or
Xmas tree: (lines of dermatomes)
Management of pitryasis rosea
Rash clears up in about six to twelve weeks
• shower with plain water and bath oil, aqueous cream,
• Apply moisturising creamsto dry skin
Medical
-Topicalsteroid may reduce the itch
-Oral Acyclovir
- Phototherapy
Fate of lichen planus
Most lesions undergo spontaneous healing within 6m with post inflammatory hyperpigmentation.
What are the sites that lichen planus commonly affect?
Skin, mucosa, nails, hair
What is the difference between lichen planus lesions and lichenoid drug eruptions
Lichenoid eruptions lack wickham stria
DD of pitryasis Rosea
Tinea croporis, viral exanthem
2ary syphilis
Seborrheic dermatitis
Fate of pitryasis Rosea
Heals spontaneously within 2 months
