derm Flashcards
tx acne vulgaris
tretinoin
benzoyl peroxide
azelaic acid
salicylic acid
erythromycin or clindamycin (topical)
doxycycline or sulfamethoxazole (oral)
isotretinoin 20 weeks if severe and unresponsive to others ^^
tx treatment resistant acne (before isotretinoin)
spironolactone
combo oral BC
what acne meds are C/I in pregnancy
tretinoin
isotretinoin
doxy
MC premalignant skin condition
actinic keratosis (may progress to squamous cell CA)
what should you do when you see actinic keratosis
punch or shave biopsy
alopecia areata is thought to be due to
underlying autoimmune disease
PE alopecia areata
smooth, non scarring hair loss w patches of smaller hairs termed exclamation hairs
tx alopecia areata
intralesional corticosteroids
MC type of skin cancer in US
basal cell CA
sx basal cell CA
small, raised papule that are pink, white or flesh colored; translucent, waxy, or pearly quality with raised “rolled” borders and central depression and/or ulceration with overlying telangiectatic surface vessels
bleeds easily
dx basal cell CA
punch or shave biopsy
what topical can you use for basal cell CA
Imiquinod
sx bullous pemphigoid
pruritus w eczematous or urticarial plaques followed by multiple tense large bullae (1-3 cm) that don’t rupture easily
PE bullous pemphigoid
negative Nikolsky - no epidermal detachment
dx bullous pemphigoid
skin biopsy w direct immunofluorescence - linear C3 and IgG along the dermal epidermal junction sub epidermal blisters, and eosinophilia
MC cause cellulitis
Group A strep (MC)
staph aureus
RF cellulitis
skin inflammation (abrasion)
lowered immunity
skin infection (tinea, rash)
edema
obesity
recent surgery or trauma or animal bites
sx cellulitis
localized macular erythema (flat margins not sharply demarcated)
swelling
warmth
tenderness
Tx cellulitis
Nafcillin, cefazolin, clindamycin, dicloxacillin, cephalexin, doxycycline, and trimethoprim-sulfamethoxazole
MC cause condyloma acuminata
HSV 6 and 11
tx condyloma acuminata
resolution w/in 18 mos
Imiquimod or Pdophyllotoxin or Sinecatechins
cryotherapy, trichloroacetic acid, surgical removal
atopic dermatitis is also called
eczema
eczema/atopic dermatitis sx
pruritus is hallmark and required for dx
erythematous, ill-defined blisters, papule, or plaques w oozing
lesions dry and crus over and scale
MC ON FLEXOR SURFACES
tx eczema/atopic dermatitis
topical corticosteroids
skin hydration
pathophysiology seborrheic dermatitis
increased sebaceous gland activity + hypersensitivity to malassezia furfur
seborrheic dermatitis is associated w what neurologic dz
parkinson dz
HIV
sx seborrheic dermatitis
erythematous plaques or patches covered w fine white-yellow greasy scales
common in areas w high sebaceous gland secretion (scalp - dandruff), eyelids, beard, mustache, nasolabial folds, chest, groin
tx seborrheic dermatitis
anti fungal shampoo
low potency topical corticosteroids, topical anti fungal agents for face
oral anti fungal if resistant
sx dyshidrotic eczema
sudden onset of pruritic “tapioca-like” small tense vesicles on the soles, palms, fingers (lateral aspect of digits)
tx dyshidrotic eczema
Topical corticosteroids
MC cause erysipelas
Group A strep (S. pyogenes)
sx erysipelas
intensely erythematous, raised area with sharply demarcated borders
MC involves lower extremities and face
often associated w systemic manifestations
MC cause erythema multiforme
herpes simplex virus (MC)
mycoplasma spp (esp in kids)
meds that can cause erythema multiforme
sulfa drugs
beta-lactams
phenytoin
phenobarbital
erysipelas
a variant of cellulitis (more superficial infxn)
sx erythema multiforme
target lesions hallmark finding - a dusky, central area or blister, a dark red inflammatory zone surrounded by a pale ring of edema, and an erythematous halo on the extreme periphery of the lesion
negative nikolsky sign
sx erythema multiforme
target lesions hallmark finding - a dusky, central area or blister, a dark red inflammatory zone surrounded by a pale ring of edema, and an erythematous halo on the extreme periphery of the lesion
negative nikolsky sign
minor - no mucosal membrane involvement
major - mucosal membrane involvement
tx erythema multiforme
supportive
remove offending drugs
topical steroids, antihistamines, analgesics, skin care etc
prophylactic acyclovir if recurring
erythema infectiosum is also called
fifth disease
erythema infectiosum is caused by
parvovirus B19
sx erythema infectiosum
erythematous malar rash “slapped cheek: and circumoral pallor
lacy, reticular maculopapular rash on extremities
may have arthropathy or arthralgias
associated w fetal loss
tx erythema infectiosum
supportive
cause of rubeola
measles virus
sx rubeola
high fever + cough, coryza, conjunctivitis
kopek spots - small 1-3 mm pale white or blue papule w an erythematous base on the buccal mucosa
morbilliform maculopapular brick-red rash beginning at the hairline
cause of hand, foot, mouth dz
coxsackie virus (esp type A)
sx hand, foot, mouth dz
oral - erythematous macula’s that become painful oral vesicles surrounded by a thing halo of erythema
exanthema - grayish-yellowish vesicular, macular, or maculopapular nonpruritic contender skin lesions on distal extremities (includes palms and soles)
roseola infantum is caused by
HHV 6