Depressive Disorder Flashcards
On average, __% of people with mental conditions also have a medical condition.
68%
On average, __% of people with medical conditions also have a mental condition.
29%
A pervasive, sustained feeling tone that is largely an internal experience and influences one’s behavior and perception is referred to as a(n) (mood/affect).
Mood
A mood is akin to an area’s “climate”. It is unseen and affects the area’s external changes.
The external expression of a sustained feeling tone that may be observed is referred to as a(n) (mood/affect).
Affect
An affect is comparable to an area’s weather. Weather is largely affected by a region’s climate. An affect is what one’s mood brings about. It is observable by those around the patient experiencing a bad mood.
Nearly all depressed patients have considerable _____________.
Anxiety
On average, depression encompasses ___% of total DALYs caused by disease.
4.3
________________ has the highest lifetime prevalence of any psychiatric disorder.
Major Depressive Disorder (MDD)
The typical onset for MDD is between __-__ years of age.
20-40
The rate of concordance among monozygotic twins experiencing MDD is __-__%.
40-50%
The rate of concordance among dizygotic twins experiencing MDD is __-__%.
10-25%
What are some of the common risk factors for depression?
- Family history
- Stressful life events
- History of anxiety
- Postpartum period
- Female gender
- Older age
- Lack of social support
- Single
- Divorced/Widowed
- Substance abuse
- Chronic pain
- Medical comorbidities
The medical condition with the highest incidence of depression as a comorbidity is ____________.
Stroke
What are some of the common risk factors for completed suicide?
- Male gender
- Over age 45
- Caucasian
- Divorced/widowed/separated
- Substance use disorders
- Previous suicide attempts
- Chronic pain
- Medical illness
- Psychotic symptoms
- Unemployed
Often times, _______________________ serves as the highest risk factor of depression.
Losing a parent as a child
The prefrontal cortex is associated with (goal directed behavior/attention and emotional arousal/emotional learning/emotional stimuli).
Goal directed behavior
The amydala is associated with (goal directed behavior/attention and emotional arousal/emotional learning/emotional stimuli).
Emotional stimuli
The anterior cingulate cortex is associated with (goal directed behavior/attention and emotional arousal/emotional learning/emotional stimuli).
Attention and emotional arousal
The hippocampus is associated with (goal directed behavior/attention and emotional arousal/emotional learning/emotional stimuli).
Emotional learning
Increased cortisol results in feedback inhibition of the _____________ and _____________.
Anterior pituitary and hypothalamus
Increased cortisol levels cause a shrunken ______________.
Hippocampus
Genetic mutations in what three proteins result in increased risk of depression?
- 5HTT (Serotonin transporter) - Serotonin transport
- Brain-derived neurotrophic factor (BDNF) - Protects cells from apoptosis in nervous tissue
- Tryptophan hydroxylase - Serotonin production