Depression/Bipolar Flashcards
A mental disorder characterized by two weeks of at least 5 of the following symptoms:
Low mood or anhedonia (lack of interest/pleasure) + SIG E CAPS
Major Depressive Disorder
Depression has low levels of what NTs
NE
Dopamine
Serotonin
Mania has (high/low) dopamine and (high/low) GABA
High dopamine
Low GABA
Anxiety has (high/low) GABA and Serotonin and (high/low) NE
Low GABA and Serotonin
High NE
What can cause Major Depressive Disorder
Hypothyroidism Anemia HIV Cushing's Bipolar Disorder Substance-induced Personality Disorders
Sleep changes associated with Major Depressive Disorder
Difficulty going to, or maintaining, sleep
Some sleep too much
Very little slow-wave; earlier into REM but increased REM duration
Depression that is caused by using alcohol, drugs, or medications (or withdrawal)
Substance-Induced Mood Disorder
- IFN-a
- alcohol
- Benzodiazepines
- Long-term corticosteroids
Treatment for treatment-resistant depression; most effective treatment so far; can result in headaches, muscle aches and memory loss
Electroconvulsive therapy
A mood disorder of at least one week of mania + at least 3 of DIG FAST.
Bipolar 1 Disorder
7 key symptoms of mania
DIG FAST
D: Distractible
I: Impulsive
G: Grandiosity
F: Flight of Ideas
A: Activity increased
S: Sleep decreased
T: Talkative
What are the differential diagnoses of Bipolar disorder 1?
Hyperthyroidism
Substance-induced mood disorder (amphetamines, high dose steroids, cocaine)
Other personality/mood disorder
Mood disorder with one major depressive episode + one HYPOMANIA episode (4 days instead of 1 week like in mania)
Bipolar disorder 2
Bipolar disorder 2 is most commonly associated with what other psychiatric illness?
anxiety
Lifetime risk of suicide in individuals with ______________ disorder is 15x that of the general population
Bipolar
The risk factors for suicide
SADPERSONS
