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HBHD > Antipsychotics > Flashcards

Antipsychotics Flashcards

1
Q

(1st/2nd) generation antipsychotics are high affinity for Dopamine (D2) antagonists

A

1st generation

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2
Q

(1st/2nd) generation antipsychotics are potent Serotonin (5HT-2) antagonists

A

2nd generation

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3
Q

Highest potency 1st generation antipsychotic

A

Haloperidol

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4
Q

Antipsychotics are used for treating what? (2 total)

A

Schizophrenia

Schizoaffective disorder

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5
Q

BEST antipsychotic for shizophrenia, but is clinically limited due to life-threatening side effects (agranulocytosis and myocarditis)

A

Clozapine

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6
Q

All antipsychotics delay cardiac conduction (long QT) and thus pose a risk for torsade de pointes (True or False)

A

True

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7
Q

Higher potency antipsychotics, like Haloperidol, have (more/less) extrapyramidal symptoms

A

More (and low potency drugs have more anticholinergic effects)

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8
Q

Extrapyramidal side effect of antipsychotics; ustained contraction of muscles, usually the neck, mouth or tongue

A

Dystonia

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9
Q

Antipsychotics most at fault for Hyperprolactinemia

A

Haloperidol (1st generation)

Risperidone (2nd generation)

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10
Q

(1st/2nd) generation antipsychotics are associated with metabolic side effects, such as weight gain, hyperlipidemia, diabetes and hypertension

A

2nd generation

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11
Q

Symptoms of Neuroleptic Malignant Syndrome

A 
Flushing
Unstable vitals
Rigidity
Encephalopathy
Enzymatic effects
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12
Q

Balancing risks and benefits, (1st/2nd generation) antipsychotics are first-line agents for psychosis

A

2nd generation (less risk of EPS, though they do have metabolic syndrome)

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13
Q

Indications for Benzodiazepines (6 total)

A 
Status epilepticus
Anxiety
Insomnia
Pre-anesthetic
Alcohol withdrawal
Panic disorder
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14
Q

Side effects of Benzodiazepines

A 
Drowsiness
Memory loss
Potential for abuse
Respiratory depression
Teratogen
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15
Q

Short acting Benzodiazepines (4 total)

A 
ATOM
A: alprazolam
T: temazepam
O: oxazepam
M: midazolam
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16
Q

3 Benzodiazepines that DO NOT require hepatic processing, have no active metabolites and are short acting (good for elderly patients and those with liver impairments)

A

Oxazepam
Lorazepam
Temazepam

HBHD (21 decks)

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