Alcohol & Substance Use Disorders Flashcards
Due to the recent ingestion of alcohol; clinically problematic behavioral or psychological changes (slurred speech, incoordination, unsteady gait, nystagmus, coma, etc.)
Alcohol Intoxication
Cessation (or reduction in) alcohol that has been heavy and prolonged; involves autonomic hyperactivity (sweaty, tachycardia), hand tremor, insomnia, hallucinations, seizures, etc.
Alcohol Withdrawal
Problematic pattern of alcohol use leading to clinically significant impairment or distress; involves large binges, persistent desire to cut down or control (usually unsuccessful), craving, desire and inability to complete obligations at work, school or home
Alcohol Use Disorder
Numerical definitions of at-risk drinking per gender
Female: >3 drinks (one sitting) or 7/week
Male: >4 drinks (one sitting) or 14/week
What does the Alcohol Screening mnemonic CAGE mean
C: Cut down?
A: Annoyed by others commenting?
G: Guilt associated?
E: Eye opening drink in the morning?
What does the Alcohol Screening mnemonic CRAFFT mean?
C: Car (drive with anyone intoxicated) R: Relax (use to relax) A: Alone (drink/use alone) F: Family or Friends (tell you to cut down) F: Forget (things while drinking) T: Trouble?
What labs are elevated with Alcohol consumption
LFT (GGT, AST, ALT)
HDL
LDH
Uric Acid
Consequence of alcohol withdrawal; onset is 2-4 days after last drink; hyperactivity, tachycardia, HTN, fever, halluinations and disoriented; CAN BE FATAL
Delirium Tremens
Triad of confusion, ataxia and ophthalmoplegia (paralysis of eye muscles); can also see Korsakoff’s Syndrome; due to dec. thiamine (Vitamin B1); EMERGENCY as 20% of untreated patients will die; MUST give Thiamine before glucose
Wernicke’s Encephalopathy
Potential consequence of Wernicke’s Encephalopathy; impaired memory in an otherwise alert, responsive patient; either retrograde or anterograde memory loss or confabulations
Karsakoff Syndrome
Delirium Tremens (in alcohol withdrawal) is due to a deficiency in what vitamin
Vitamin B1 (Thiamine)
Treatment for Delirium Tremens
Benzodiazepines (long acting)
Thiamine
Folate
What if your Delirium Tremens patient starts to seize? (what treatment)
Benzodiazepines
What if your Delirium Tremens patient starts to hallucinate?
Haloperidol (low dose)
Examples of treatment for Alcohol Dependence (pharmacologic)
Disulfiram
Acamprosate
Naltrexone