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Pharmacology 💊 > Dementia > Flashcards

Dementia Flashcards

1
Q

MoA of Acetylcholinesterase inhibitors

A

reduce breakdown of ACh, more ACh in synapse

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2
Q

Donepezil

A

Acetylcholinesterase inhibitor

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3
Q

Most common side effects of Acetylcholinesterase inhibitors

A

GI side effects: nausea, vomiting, diarrhoea

headacheas

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4
Q

Contraindications with use of Acetylcholinesterase inhibitors

A

History of seizures – lowers seizure threshold

Arrhythmias – can cause bradycardia

Peptic ulcer disease – increased risk of bleeding

Asthma - exacerbates airway diseases

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5
Q

MoA of Memantine

A

NMDA antagonist - blocks effect of XS glutamate

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6
Q

Side effects of Memantine

A
  • sleepiness/sedation
  • headache
  • dizziness
  • can reduce seizure threshold
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Pharmacology 💊 (13 decks)

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