Dementia Flashcards
________ is by far the most common cause of dementia.
Alzheimer disease
There are 4 test you should get while suspecting Dementia
MRI of brain
VDRL or RPR to exclude syphilis
B12 with possible methylmalonic acid level
Thyroid function test
What kinds of dementia have diffuse symmetrical atrophy on MRI?
Alzheimer disease
chronic alcoholism, and
untreated HIV
This MRI Dx related with dementia symptoms has Qx management
Draining a chronic subdural hematoma (right) may improve memory.
Dementia Treatment
Donepezil, rivastigmine, and galantamine are equal in efficacy. All increase acetylcholine levels.
Memantine
Lewy Body Dementia is
Associated with
Parkinson disease
Treat both Parkinson disease and Alzheimer disease with
levodopa/ carbidopa
In Frontotemporal Dementia you can notice that _______ and _____________ are lost first. And _______ later
Emotional and social appropriateness
Memory deteriorates
Frontotemporal Dementia Tx
No special therapy beyond acetylcholine medications
Creutzfeldt-Jakob Disease clinically is characterized by: ____ + this sign
Rapidly progressive dementia
Myoclonic jerks
Creutzfeldt-Jakob Disease imaging studies show
nothing. MRI or CT are normal
Creutzfeldt-Jakob Disease CSF shows
14-3-3 protein
Creutzfeldt-Jakob Disease most accurate test
cortical brain Biopsy.
It shows spongiform degeneration, which is the result of neuronal loss and the formation of numerous vacuoles
Creutzfeldt-Jakob Disease Tx
No specific therapy
