Acute Inflammatory Polyneuropathy (Guillain-Barré Syndrome) Flashcards
It is is an ____ damage of ________.
autoimmune
multiple peripheral nerves.
T/F there is CNS involvement.
F
A circulating ____ attacks the______ of the peripheral nerves, removing their _____-
antibody
myelin sheaths
insulation.
GBS is associated with _______ infection.
Campylobacter jejuni
“What Is the Most Likely Diagnosis?” 2 CxFx
weakness in the legs that ascends from the feet and moves toward the chest,
+
loss of DTRs.
a few Pt have this sign
mild sensory disturbance.
when GBS hits the diaphragm, it is associated with
respiratory muscle weakness
This other manifestations car occur
Autonomic dysfunction
+
hypotension, hypertension, or tachycardia
The most specific diagnostic test is
nerve conduction studies/electromyography.
These will show a decrease in the propagation of electrical impulses along the nerves, but it takes 1–2 weeks to become abnormal
CSF shows
increased protein with a normal cell count
Tests of Respiratory Muscle Involvement?
show?
PFTs. tell who might die from GBS
When the diaphragm is involved, there is a decrease in forced vital capacity and peak inspiratory pressure. Inspiration is the “active” part of breathing and the patient loses the strength to inhale.
Death from GBS, how, why?
from dysautonomia and respiratory failure
Treatment
Intravenous immunoglobulin (IVIG) or plasmapheresis are equal in efficacy
when to use Prednisone
Never in GBS, is a wrong answer.
what about Combining IVIG and plasmapheresis
wrong answer.
