Degenerative conditions Flashcards

1
Q

What is osteoarthritis

A

A disease of synovial joints in which the articular cartilage becomes split, fissured and softened and gradually resorbs tsometimes down to underlying bone

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2
Q

What is the name given to the spurs of bone that are formed in osteoarthritis

A

Osteophytes

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3
Q

Describe the changes seen in osteoarthritis

A

Softening and splitting of articular cartilage (fibrillation)

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4
Q

What might be responsible for collagen break down

A

matrix metalloproteinases

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5
Q

What are some secondary causes of osteoarthritis

A
Fractures 
joint infection 
inflammatroy joint disease
congenital abnormalities
joint instability 
cartilage damage
obesity
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6
Q

What are the 3 main symptoms of osteoarthritis

A

stiffness - after rest, causes difficulty in every day tasks
swelling - overproduction of under-absorption of synovial fluid or from osteophyte formation
deformity - as a result of soft tissue changes such as muscular spasm
Pain - exacerbated by exercise

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7
Q

Describe the changes seen when examining the movement of a joint with OA

A

restricted
muscle spasma and pain
crepitus

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8
Q

What are the radiological signs of OA

A

narrowing of the joint space
osteophyte formation around the edges of the joint
sclerosis in the subchondral bone
cysts in the subchondral bone

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9
Q

What are the mainstay of treatment in OA

A

analgesics

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10
Q

How can the patient protect their joint

A

lose weight
use a stick
splint
change of lifestyle

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11
Q

What are the surgical options for a patient with OA

A

osteotomy
arthrodesis - bones either side of the joint are jointed together permanently
arthroplasty - joint replacement
arthroscopic lavage - clearout debris, osteophytes, cartilage fragments - more a palliative procedure

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12
Q

What groupp of conditions are characterised by deterioration i the structure and strength of those tissues that contain a high proportion of collagen

A

degenerative conditions of collagenous tissues

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13
Q

What are tendinopathies

A

a group of conditions affecting the tendons themselves and are characterised by swelling, tenderness and gradual loss of function

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14
Q

How does the collagen in tendinopathy become disorganised

A

constant splitting (tendinosis) and inflammation (tendonitis) and subsequent healing

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15
Q

What eventually happens to the tendon

A

it loses its elasticity and original length

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16
Q

What is the treatment for tendinopathy

A

nest
immbolisation
sometimes a splint
rarely injection of steroid or surgery

17
Q

What is tenosynovitis

A

a condition in which a tendon sheath becomes inflamed and often distended with fluid

18
Q

What does tenosynovitis usually affect

A

the flexor or extensor tendons in the thumb or fingers where they cross the wrist within a synovial sheath

19
Q

What are example of a tenosynovitis

A

De Quervain’s disease and trigger finger

20
Q

What is the treatment of Tenosynovitis

A

change in occupation

immobilisation for 2-3 weeks in a plaster cast to prevent thumb or finger movements

21
Q

What does the young intervertebral disc consist of

A

a ell demarcated nucleus pulposus and annulus fibrosus

22
Q

What happens to the disc in intervertebral disc degeneration

A

it loses its elasticity and ability to act as a shock absorber and the disc space becomes narrowed and distorted

23
Q

What is a disc prolapse

A

The nuclear material bursts through the annulus particularly during lifting or straining

24
Q

what happens in capsulitis

A

The collagen of the joint capsule may give way and become inflamed

25
Q

If capsulitis is chronic in the shoulder, what is it known as

A

Frozen shoulder

26
Q

What does a ganglion present as

A

a cystic swelling occurring in relation to a joint or tendon sheath

27
Q

Where are ganglia particularly common

A

on the dorm of the hand and wrist and around the ankle

28
Q

Describe the appearance of a ganglion

A

non tender
fluctuant
tranilluminable

29
Q

Why do ganglions arise

A

by a protrusion of synovium or synovial fluid through a microscopic split i the capsule or fibrous sheath

30
Q

What is the treatment for a ganglion

A

may disperse by a blow or pressure but may also be aspirated

31
Q

What must be excised if recurrence is to be avoided with ganglions

A

the neck of the ganglion