deck_2671190 Flashcards

1
Q

Chronic Inflammation

A

Inflammation of prolonged duration or slow progress marked histologically by an infiltration of mononuclear cells (lymphocytes, macrophages, plasma cells) often with proliferation of fibroblasts and fibrosis

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2
Q

Chronic Pyelonephritis

A

Chronic inflammation of the kidney involving the tubules and interstitium which results in scarring

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3
Q

Crohn’s Disease

A

A recurrent granulomatous and chronic inflammatory disorder that usually affects the terminal ileum or colon but may occur at any level of the GI tract; results in extensive scarring and fistulae

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4
Q

Diverticulitis

A

Trapping of fecal material within the diverticular pouch leads to bacterial overgrowth which provokes an inflammator response

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5
Q

Diverticulosis

A

A colonic disease associated with increasing age in whcih small pockets of mucosa protrude through the muscular wall

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6
Q

Giant Cells

A

Fused macrophages with very large cytoplasm and multiple nuclei; Two types (Langhans horshoe arranged nuclei) (Foreign body clustered or random nuclei)

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7
Q

Granulation Tissue

A

so called because grossly, under the scab, it has a granular appearance; characterized by ingrowth of new blood vessels and scar tissue

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8
Q

Granuloma

A

A specific form of chronic inflammatory response to antigens that cannot be eliminated during the acute inflammatory response; characterized histologically by collections of epitheloid macrophages, rim of lymphocytes, giant cells, and caseus necrosis

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9
Q

Healing by primary intention

A

healing, following surgical closure, or a wound where the edges are naturally brought together so that only a minimum amount of scar formation occurs

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10
Q

Healing by secondary intention

A

healing, without the intervention of a surgeon, of a large open wound, leading to extensive scarring

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11
Q

Keloid

A

and exaggerated form of scar that protrudes upward from the skin that is characterized by the presence of dense connective tissue (more prevalent in african americans)

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12
Q

Miliary

A

Multiple minute deposites that resmeble “millet seeds”

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13
Q

Scar

A

A collection of collagen that is the end result of repair of an injury

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14
Q

Ulcer

A

A local tissue defect, or excavation involving the epithelial surface of an organ or tissue (think healing by secondary intention)

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