Decadron (Dexamethasone)

Question 1

Decadron (Dexamethasone) class

Answer 1

Glucocorticoid

Question 2

Decadron (Dexamethasone) MOA

Answer 2

Believed to reduce sx induced inflammation d/t inhibition of prostaglandin synthesis

Exerts anitemetic effects by increasing release of endorphins resulting in mood elevation/appetite stimulation

Question 3

Decadron (Dexamethasone) dosage

Answer 3

IV: 4-8 mg

Peds: 150mcg/kg up to 8mg

Question 4

Decadron (Dexamethasone) characteristics

Answer 4

O: IV/IM 10-30 min

P: IV: 5-10 min

D: 36-54 hrs)

Question 5

Decadron (Dexamethasone) E/M

Answer 5

M: hepatic

E: renal

H/t: 3.5-5 hrs

Question 6

Decadron (Dexamethasone) considerations

Answer 6

Decreases cerebral edema associated w/ increases in ICP

Prevent PONV

Prolongs analgesia for interscalene blocks using Ropivacaine or Bupivacaine

Use caution in: ulcerative dzs, MG, renal ins, osteoporosis, latent dzs (fungal, bacterial, parasitic), diabetic