Dani - ch 16 Flashcards
gas exchange and nutrient/waste product exchange occurs between blood int he ___ and the tissues
microcirculation
microcirculation primarily includes the ___ to ____square meters of capillaries
500-700
terminal areterioles are called ____
metarterioles
metarterioles are where the arterioles branch down to the ___
capillary
where the metarteriole meets the capillary, the SM fibers form the ___ ___ which can open or close the opening of the capillary
precapillary sphincter
___ ___ of the tissues controls the blood flow according to tissue needs because the metarteriole and precapillary sphincter are close in contact
local conditions
control of blood flow is based on ___ or ___ the diameter of the blood vessel
increasing
decreasing
___ ____: single celled, highly permeable layer of endothelium surrounded by a thin basement membrane
capillary wall
___ between individual cells that make up the capillary wall allow for small nutrient molecules and plasma fluid to leave the capillary
pores
blood cells and plasm are too ___ to fit through the pores
big
___ ___: thing, curving channels between cells
intercellular cleft
water, water-soluble ions and small solutes can ___ through intercellular clefts
diffuse
___: formed on the cell membrane from proteins associated with cholesterol and other lipid materials
caveolae
caveolae play a ___ role by engulfing small packets of plasm, or extra cellular fluid with plasma proteins, and transporting it slowly through the endothelium
transcytosis
brain has ___ ___ only allow extremely small molecules in or out
tight junction
liver - has ___ pores so that even plasm proteins can pass
large
GI tact - ___ than liver but ___ than brain
smaller
larger
kidney - contain windows called ___ which also tremendous amounts of small ions, but not large plasma proteins, to pass so the kidneys can filter blood rapidly
fenestrae
___ is the type of blood flow through the capillaries
vasomotion
blood flow is not ___, it flows ____
continuous
intermittently
the cause of vasomotion is intermittent opening and closing of ___ and ___ ___
metarterioles
precapillary sphincters
regulation of vasomotion is primarily controlled by the ___ concentration in the tissues
oxygen
when tissues use oxygen at a greater rate, oxygen concentration ____ thus intermittent periods of floow occure ___ often
decrease
more
___ is the primary method of transfer of water and dissolved ions between the capillaries and interstitial space
diffusion
____ ___: space between cells and contains the fluid that provides a water environment for cells
interstitial space
diffusion results from the ___ ___ of water molecules and dissolved ions as they randomly move in all directions between the capillary membrane and the interstitial space
thermal motion
lipid soluble substances has an effect on ___
diffusion
lipid soluble substances can diffuse ____ through the capillary membrane and dont have to go through the ___
directly
pores
lipid soluble substances are ___ and ____
oxygen
carbon dioxide
lipid soluble substances - because they can diffuse directly across the membrane, they can diffuse at a much ___ rate than lipid- insoluble substances
faster