cytoskelton part two Flashcards
What do all these motor proteins share in common both structurally, and functionally?
Kinesin, Dynein, and the Myosin Family.
motor proteins all convert the energy from ATP into force and movement on either the actin or microtubule tracks.
Kinesin and dynein transport biological payloads, such as proteins, organelles, and vesicles, along microtubule pathways, and provide forces to drive motion of flagellar structures and cilia
Both have ATP binding heads and a single tail
For Kinesin and Dynein, what is their major role in the cytoplasm?
Kinesin role: move towards the plus end
Dynein role: moves on the minus end
transportation of larger vesicles and proteins
What is the basic cytoskeletal structure of Cilia
Cilia:
has arrangement of microtubules. made up of 9 doublets in pairs of two
Flagellum:
Same structure at cilia (9 microtubules doublets around a central doublet. . 4x longer and in a rippling motion. It moves itself, not the surrounding
w are they similar to Centrioles?
They also have 9 triplets of microtubels. These are the ones radiating out
What role does Dynein play in the function of Cilia and Flagella?
movement, walk down
What roles do Myosin I play in the cell?
Actin uses different motor protein - myosin
Myosin 1- globular head with tail that attaches to stuff
Individual myosin ones attached to a vesicle on a actin filament
Myosin walk to plus ends
Actin capped at plus end that prevents it from moving
One configuration. Feet attachment to actin filament
We can also be bound to plasma membrane.
Myosin II :
Myosin 2: dimer of myosin’s
In a muscles cell, dimer aggrgate come togthe to form myosin filaments
Bottoms of filaments meet to form filament
Be able to describe the main structural features of a Muscle Cell.
Made up of skeletal muscle- actic and myosin 2 from think structures called myofibril
What are the roles of the Transverse Tubules and Sarcoplasmic Reticulum?
Where are they located within a muscle fiber?
Sacroplastic reticulum- form of smooth er that functions to store Ca ons
Transverse tubels: tubles that bring th eoutside into the muscle
Tropomyosin
rigid protein that winds around Actin filaments. Inhibits myosin heads from binding with actin