Cytokines, Interferons, Cell Surface Molecules I Flashcards

1
Q

What type of cells possess CD1 antigens?

A

DC cells.

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2
Q

What is the function of CD1 cells?

A

MHC Class I like; presents lipid antigen.

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3
Q

What types of cells possess CD2 antigens?

A

T cells, NK cells, Thymocytes

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4
Q

What is the function of CD2 cells?

A

Adhesion molecules that bind to CD58 to assist in T cell activation

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5
Q

What types of cells possess CD3 antigens?

A

T cells, thymocytes.

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6
Q

What is the function of CD3 cells?

A

Signal transduction associated with TCRs.

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7
Q

What types of cells possess CD4 antigens?

A

Th1 and Th2 cells, monocytes, macrophages.

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8
Q

What is the function of CD4 cells?

A

Co-receptor that docks to MHC class II and assists in T cell activation.

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9
Q

What types of cells possess CD8 antigens?

A

Cytotoxic T cells.

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10
Q

What is the function of CD8 cells?

A

Co receptor that docks to MHC I and assists in T cell activation.

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11
Q

What types of cells possess CD11 antigens?

A

Lymphocytes (granulocytes, monocytes, macrophages); myeloid cells (NK cells); leukocytes.

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12
Q

What type of cells is distinguished by CD14 antigens?

A

Macrophages.

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13
Q

What types of cells possess CD16 antigens?

A

Neutrophils, NK cells, Macrophages.

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14
Q

What CD antigen cell type mediates endocytosis?

A

CD16.

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15
Q

What types of cells possess CD18 antigens?

A

Leukocytes

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16
Q

What CD markers distinguish B cells?

A

CD19, CD21, CD23, CD35, CD82L, CD80

17
Q

What CD antigen cell type is a low affinity receptor for IgE?

A

CD23

18
Q

What CD markers distinguish activated B cells?

A

CD25, CD28, CD86

19
Q

What CD marker distinguishes activated T cells?

A

CD25

20
Q

What CD markers are possessed by both B and T cells?

A

CD25, CD28

21
Q

What CD marker represents the alpha subunit of the IL-2 receptor?

A

CD25

22
Q

What types of cells possess CD35 antigens?

A

B cells, monocytes, neutrophils, eosinophils, DCs.

23
Q

What is the function of the CD35 antigen?

A

Complement receptor 1 and mediation of phagocytosis.

24
Q

What CD marker is expressed by all hematopoietic cells?

A

CD45

25
Q

What is the function of CD45 cells?

A

To mediate lymphocyte activation