Cytokines, Interferons, Cell Surface Molecules I Flashcards
What type of cells possess CD1 antigens?
DC cells.
What is the function of CD1 cells?
MHC Class I like; presents lipid antigen.
What types of cells possess CD2 antigens?
T cells, NK cells, Thymocytes
What is the function of CD2 cells?
Adhesion molecules that bind to CD58 to assist in T cell activation
What types of cells possess CD3 antigens?
T cells, thymocytes.
What is the function of CD3 cells?
Signal transduction associated with TCRs.
What types of cells possess CD4 antigens?
Th1 and Th2 cells, monocytes, macrophages.
What is the function of CD4 cells?
Co-receptor that docks to MHC class II and assists in T cell activation.
What types of cells possess CD8 antigens?
Cytotoxic T cells.
What is the function of CD8 cells?
Co receptor that docks to MHC I and assists in T cell activation.
What types of cells possess CD11 antigens?
Lymphocytes (granulocytes, monocytes, macrophages); myeloid cells (NK cells); leukocytes.
What type of cells is distinguished by CD14 antigens?
Macrophages.
What types of cells possess CD16 antigens?
Neutrophils, NK cells, Macrophages.
What CD antigen cell type mediates endocytosis?
CD16.
What types of cells possess CD18 antigens?
Leukocytes
What CD markers distinguish B cells?
CD19, CD21, CD23, CD35, CD82L, CD80
What CD antigen cell type is a low affinity receptor for IgE?
CD23
What CD markers distinguish activated B cells?
CD25, CD28, CD86
What CD marker distinguishes activated T cells?
CD25
What CD markers are possessed by both B and T cells?
CD25, CD28
What CD marker represents the alpha subunit of the IL-2 receptor?
CD25
What types of cells possess CD35 antigens?
B cells, monocytes, neutrophils, eosinophils, DCs.
What is the function of the CD35 antigen?
Complement receptor 1 and mediation of phagocytosis.
What CD marker is expressed by all hematopoietic cells?
CD45
What is the function of CD45 cells?
To mediate lymphocyte activation
