Cytokines Flashcards
1
Q
IFN-gamma
A
Activates Macrophages
2
Q
IL-2
A
Activates T Cell clonal expansion
3
Q
IL-4
A
Class switching from IgG to IgE
4
Q
IL-5
A
Stimulates eosinophil production in the bone marrow
5
Q
IL-13
A
ASTHMA CYTOKINE
Biggest role is working with mast cells to establish the hyper-responsive state in smooth muscle
6
Q
IL-10
A
stimulate TH2
inhibit TH1
7
Q
What do TH2 cells produce under allergy response?
A
IL-4
IL-5
IL-13
8
Q
TH1 transcription factors
A
STAT-1
T-BET
9
Q
what does TH1 secrete?
A
IFN-gamma –> inhibits TH2
10
Q
TH2 transcription factors
A
STAT-6
GATA-3
NF-AT
11
Q
What does TH2 secrete?
A
IL-10 –> inhibits TH1
IL 4/5/13
