Cytokines Flashcards
Function: inflammation and fever
Produced by: APC and various cells
IL-1
Function: T, B, and NK activation
Produced by: Th1 and Nk
IL-2
Function: hematopoiesis
Produced by: T cells
IL-3
Function: B cell and Th2 cell activation
Produced by: Th2 cells
IL-4
Function: B cell activation
Produced by: Th2 cells
IL-5
Function: Inflammation
Produced by: T cells and APC
IL-6
Function: T and B cell development
Produced by: Bone marrow
IL-7
Function: chemotaxis of neutrophils
Produced by: APC
IL-8
Function: cell activation or suppression
Produced by: Th2
IL-10
Function: Th1 cell activation
Produced by: APC
IL-12
Function: Increase MHC expression
Produced by: T cell and NK cells
IFN- gamma
Function: Inflammation and fever
Produced by: T cells and APC
TNF- alpha
Function: hemaptopoiesis
Produced by: T cells and APC
GM-CSF
Function: Enhance MHC expression and antiviral
Produced by: various cells
IFN-alpha and IFN-beta