Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Dermatology Board Prep > DERM (18) Skin Growths > Cysts > Flashcards

Cysts Flashcards

1
Q

What cysts have a granular layer?

A

EIC dialted pore of Winer, milia, pilar sheath acanthoma, dermoid cyst, eruptive vellus hair cyst, verrucous epidermal cyst, pigmented follicular cyst +/- steatocytoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Differentiation between EIC and millia?

A

<3mm = milia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Pathology of EIC?

A

Cystic cavity w/ laminated keratin w/ stratified squamous epithelium w/ granular layer. NO ADNEXAL STRUCTURES IN WALL like vellus hair cyst or dermoid cyst

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Associations with EIC?

A

Gardners syndrome, Basal Cell Nevus Syndrome, multiple cysts can lead to scrotal calcinosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What meds lead to EIC?

A

BRAF inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Pathology of a dilated pore of Winer?

A

Lined by a granular layer, ancathotic finger-like projections pushing into the dermis. Squamous epithelium.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Difference between pilar sheath acanthoma and dilated pore of Winer?

A

Thicker epithelium with the pilar sheath acanthoma that extends further and deeper than a dilated pore of Winer.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Name of milia on the hard palate of an infant?

A

Epstein’s pearls (Bohns nodules are more lateral at the buccal and lingual dental ridges)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Describe Epstein’s pearls?

A

Keratin-filled cysts with squamous epithelial lining (like an epidermal inclusion cyst) that are often found on the palate.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What dz can lead to EIC?

A

Blistering dz like EBA and PCT –> scarring dz, going to trap some follicular structures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Path of milia?

A

Same as EIC but smaller <3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Pathology of a pilar sheath cyst?

A

They do not have granular layer, compact, keratinization analogous to that of outer root sheath of the hair follicle at the isthmus, homogenous material w/ freq foci of cacification

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are 2 categories of milia?

A

Scarring vs non scarring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Why do scarring cause milia?

A

Traps eccrine gland, contents can’t get out

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Histology of a proliferating pilar cyst?

A

Proliferating trichilemmal tumor. broad anastomosing bands and nodules of squamous epithelium, proliferation… like pilar cysts that are together

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Histology of a vellus hair cyst?

A

Has granular layer, loose laminated keratinizing with numerous vellus hairs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the most common locations of vellus hair cysts?

A

Trunk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Associated things with hair cyst?

A

Eruptive vellus hair cysts / a/w steatocystoma multiplex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Histology of steatocystoma?

A

Shark tooth lining (serrated appearing), associated w/ sebaceous gland in the wall (not always visible), loose material in the center, decapitative secretion.

Sometimes no granular layer (sources vary on this)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What associations are seen with steatocystoma?

A

Steatocystoma multiplex, associated with pachyonychia congenita type 2.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Mutation in steatocystoma multiplex?

A

Keratin 17

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Another name for pachyonychia congenita type 2?

A

Jackson-Lawler

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is the difference on histology between steatocystoma and cutaneous keratocyst?

A

Similar path to steatocystoma but w/ no sebaceous gland associated w/ it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Most common location of dermoid cyst?

A

Located around the eyes in an infant, lateral eyebrow is the m/c place

May be a/w underlying skull defect in embryonic fusion planes **don’t bx w/o imaging

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Pathology of a dermoid cyst?

A

Has granular layer, stratified squamous epithelium, contains other normal cutaneous structures such as hair (terminal hairs not vellus hairs), sebaceous lobules, eccrine, apocrine glands, smooth muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Where do ear pits come from?

A

Incomplete fusion of 3 tubercles from the first 2 branchial arches

27
Q

What is the follicular occlusion tetrad?

A
  1. acne congloblata
  2. hidradenitis suppuratie
  3. dissecting cellulits of scalp
  4. pilonidal cyst ask about other sx’s present
28
Q

What epidermal cysts have non-stratified squamous epithelium?

A

Hidrocystoma (eccrine, apocrine), bronchogenic cyst, thyroglossal duct cyst, branchial cleft cyst, cutaneous ciliated cyst, ciliated cyst of the vulva, median raphe cyst, omphalomesenteric duct cyst.

29
Q

What is the most common non-granular layer cyst?

A

Pilar cyst

30
Q

What is the most common granular layer containing cyst?

A

EIC

31
Q

What is the differentiation of a cyst if it doesn’t have a granular layer?

A

3 choices from squamous epi: pilonidal, ear pit cyst, steatocystoma (sort of) or developmental cysts

32
Q

What are the cutaneous manifestations of Schopf-Schulz-Passarge syndrome?

A

Apocrine hidrocystomas, palmoplantar keratoderma, hypotrichosis, and onychodystrophy

33
Q

Clinical of hidrocystoma?

A

BLUISH cysts, mc on face can be by the eye. apocrine or eccrine. solitary (smith) or multiple (robinson) apocrien usually solitary eccrine usually muptole

34
Q

Histology of hidrocystoma?

A

Pigmented sweat in the middle, two cell lining, not connected to epidermis usually

35
Q

What is the clinical presentation of the bronchogenic cyst?

A

2nd or 3rd decades, most often occurring on the midline near the manubrium sterni. Can present as a cyst or a draining sinus

36
Q

thyroglossal duct cyst?

A

movement w/ swallowing (dif from bronchogenic cyst), midline cystic nodules on ontaerior neckline in kids and young adults.

37
Q

branchial celft cyst clinical

A

do not move w/ swallowing, mc preauricualr, mandibular, anterior border of SCM, more lateral as compared to thyroglossal duct cyst.

38
Q

What is the clinical presentation of a median raphe cyst?

A

Most commonly located near the glans, ventral aspect of the penis, they do not connect to the urethra, can be cut out

39
Q

What is the clinical presentation of a omphalomesenteric duct cyst?

A

Vitelline cyst, failure of closure of the connection between midgut and yolk sac, may occur anywhere between intestines and umbilicus

Looks like a polyp-like structure on the umbilicus

40
Q

What is a urachal cyst?

A

Connects fetal bladder to the umbilicus, normally closes during development

Urine leakage from incomplete urachal duct remnant occurs

These can be painful, should be ultrasounded

41
Q

Treatment of urachal cyst?

A

US and you do want to excise to prevent infxn

42
Q

Mucocele clinical presentation?

A

Lower labial mucosa is the most common location, also on the floor of mouth buccal mucosa tongue

Dome-shaped, arise as a result of the disruption of ducts of minor salivary glands.

43
Q

Clinical presentation of digital mucous cyst?

A

Filled w/ mucus, on the dorsal surface of the distal finger by nail

Longitudinal depression of the nail plate may be seen distal to the lesion

44
Q

Clinical presentation of a ganglion cyst?

A

Can be attached to tendon sheath (often) do not often communicate with the joint space. mc on dorsal surface

45
Q

What is the clinical presentation of a psedocyst of the auricle?

A

Cauliflower ear, scaphoid fossa of the ear, middle-aged men, unilateral, chronic trauma is the cause.

46
Q

What cysts arise from the follicular infundibulum?

A

EIC, milium, pigmented follicular cyst, vellus hair cyst

47
Q

What cysts arise from the follicular isthmus?

A

Pilar cyst

48
Q

What cysts arise from the sebaceous ducts?

A

Steatocystoma

49
Q

What two genetic dz’s are EIC’s associated with?

A

Gardner’s syndrome and Gorlin syndrome

50
Q

What is the mutation in steatocystoma multiplex?

A

Keratin 17

51
Q

How is steatocystoma multiplex inherited?

A

AD

52
Q

What is it called when you have multiple steatocystoma w/ eruptive vellus hair cysts?

A

Pachyonychia congenita type 2

53
Q

What is the other name for pachyonychia congenita type 2?

A

Jackson Lawler

54
Q

What are the mutations in pachyonychia congenita type 2 or Jackson-Lawler syndrome?

A

keratin 6b, 17

55
Q

What syndrome is associated with hybrid cysts with pilomatrical changes?

A

Gardner’s syndrome

56
Q

What are the 3 genoderms associated w/ dermoid cysts?

A

Gorlin Syndrome, klippel-feil syndrome, goldenhar syndrom

57
Q

What is Goldenhar syndrome?

A

AR, a/w limbal-epibulbar (ocular) dermoid cysts, which are caused secondary to defects in the 1st and 2nd branchial arches, also a/w accessory tragus, auricular fistula, deafness, Golden”HARd” of hearing

58
Q

What are the non-stratified squamous epithelium lined cysts?

A

Hidrocystoma (eccrine/apocrine), bronchogenic cyst, thyroglossal duct cyst, branchial cleft cyst, cutaneous ciliated cyst, ciliated cyst of the vulva, meidan raphe cyst, omphalomesenteric duct cyst

59
Q

What is a solitary hydrocystoma called?

A

Smith hydrocystoma

60
Q

What are multiple hidrocystomas called?

A

Robinson

61
Q

What is the pathology of the omphalomesenteric duct cyst?

A

Looks like gi mucosa, must be distinguished from gi metastasis

62
Q

What cysts do not have an epithelial lining?

A

Mucocele, digital mucous cyst, ganglion cyst, pseudocyst of auricle, cutaneous metaplastic synovial cyst

63
Q

Histology of a branchial cleft cyst?

A

Pseudostratified columnar or stratified squamous epithelium with surrounding dense lymphoid tissue including lymphoid follicles w/ germianl centers (this prominent lymphoid aggregates and follicles is a key)

DERM (18) Skin Growths (17 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions