Cystic fibrosis

Question 1

CF

Answer 1

mutation is cystic fibrosis transmembrane conductance regulator (CFTR)
-abnormal transport of chloride, bicarbonate, and sodium ions

Question 2

common organisms seen in CF patients

Answer 2

staph aureus, H. influenzae followed by pseudomonas

Question 3

Inhaled medications for CF

Answer 3

1. inhaled bronchodilators (albuterol - opens airways)
2. hypertonic saline (mobilizes mucus to improve airway clearance)
3. dornase alfa (decreases the viscosity of mucus to promote airway clearance)
4. chest physiotherapy (mobilizes mucus to improve airway clearance)
5. inhaled antibiotics (controls airway infection)

Question 4

chronic pseudomonas infection

Answer 4

inhaled antibiotics
-treatment cycled with 28 days on therapy and followed by 28 days off
-tobramycin
-aztreonam
-oral azithromycin to decrease inflammation and exacerbations

Question 5

Pancrelipase (Creon)

Answer 5

helps break down fat, starches, and protein
-abdominal pain, flatulence, nausea