Acute Care Flashcards
Crystalloids
-D5W (free water)
-NS (volume resuscitation)
-LR (volume resuscitation)
Colloids
-large molecules that remain in the intravascular space and increase oncotic pressure
-albumin (edema)
hypotonic hypervolemic hyponatreia
-caused by fluid overload
-diuresis with fluid restriction
hypotonic isovolemic hyponatremia
-caused by SIADH
-diuresis, restricting fluids, and stopping drugs that can cause SIADH
hypotonic hypovolemic hyponatremia
-salt wasting, diuretics, adrenal insufficiency, blood loss, or vomiting/diarrhea
-stop hypotonic solutions
-severe symptoms/Na <120 can use hypertonic (3%) sodium
correcting hyponatremia
-should not be correct too fast (4-8 mEq/L/24h)
-correcting more rapidly than 12 mEq/L/24h can cause osmotic demyelination syndrome or central pontine myelinolysis which can cause paralysis, seizures, and death
Conivaptan and Tolvaptan
can be used to treat SIADH and hypervolemic hyponatremia
Hypernatremia
-associated with a water deficit and hypertonicity
-hypovolemic: loss of fluids > replace with fluids
-hypervolemic: hypertonic fluids > diuresis
-isovolemic: DI > desmopressin
KCl
-peripheral line: max infusion rate < 10 mEq/hr and max concentration of 10 mEq/100 mL
-higher rates/concentration require a central line and cardiac monitoring
-DO NOT IV PUSH
Resistant hypokalemia
-serum magnesium should be checked as magnesium is necessary for potassium uptake
-magnesium should be replaced first when both are present
hypomagnesium
-IV, IM magnesium sulfate
-magnesium oxide (PO)
hypophosphotemia
< 1 mg/dL treat with IV phosphorous
IVIG (Gammagard, Gamunex-C, Octagam, Privigen)
-slower infusion rate in renal and CV disease
-do not freeze, shake or heat
-Boxed Warnings: acute renal dysfunction, thrombosis
-infusion reaction (facial flushing), chest tightness, fever, chills, hypotension
Vasopressors
-most work by stimulating alpha receptors
-causes peripheral vasoconstriction and increasing systemic vascular resistance which in turn increases BP, HR, CO
-all are vesicants when administered IV –> treat extravasation with phentolamine
-arrhythmias, tachycardia, necrosis (gangrene), bradycardia (phenylephrine), hyperglycemia (epi)
-all should be administered via central line
Dopamine
-Low (renal) dose: 1-4 mcg/kg/min works at dopamine-1-agonist receptors
-medium dose: 5-10 mcg/kg/min works at beta-1-agonist receptors
-high dose: 10-20 mcg/kg/min works at alpha-1-agonist