CV Flashcards

1
Q

left vs right sided heart failure

A

right -
congestion of peripheral tissue - blood not flowing into the heart from them well enough
liver congestion - signs relating to impaired liver function
GI tract congestion - anorexia, GI distress, weight loss
oedema and ascites (modified transudate)

left -
decreased cardiac output
decreased tissue perfusion
pulmonary congestion - cough with frothy sputum, orthopnea (breathlessness lying down), nocturnal dyspnea

left failure –> right failure

chronic lung disease –> right failure

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2
Q

ventricular septal defect

A

hole in wall separating ventricles
common in cattle
left –> right shunt
pulmonary hypertension

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3
Q

atrial septal defect

A

hole in wall between atriums
left –> right shunt
right sided heart failure
ascites

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4
Q

pulmonic stenosis

A

narrowing of valve or artery from right ventricle to lungs
reduced flow to lungs
right sided heart failure

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5
Q

patent ductus arteriosus

A

failure of vessel between aorta and pulmonary artery to close
cuts out lungs
common in dogs

pulmonary hypertension, right sided heart failure

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6
Q

persistent right aortic arch

A

retained vessel
constricts oesophagus

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7
Q

tetralogy of fallot

A

combination - ventricular septal, pulmonary stenosis, overriding aorta and right ventricular hypertrophy (VPAH - very poorly animal heart)

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8
Q

mitral valve disease

A

small breeds - cavvys and sausages
regurgitation and systolic dystfunction (mitral valve closure)

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9
Q

dilated cardiomyopathy

A

large breeds - doberman and great dane
weak myocardium, big floppy heart, low cardiac output

right and left sided failure - left ventricle gets bigger filling and not pumping, back flow into atrium
chamber dilation and thinning of wall
ststolic failure

in cats - taurine deficiency in diet

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10
Q

arrhythmia

A

any abnormal rhythm
untreated can lead to cardiac failure or organ dysfunction

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11
Q

signs of cardiorespiratory disease

A

coughing
breathlessness
lethargy
exercise intolerence
murmur
collapse
weight loss
abdominal swelling/peripheral oedema

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12
Q

cardiac failure

A

cv system unable to provide enough flow for metabolic needs
usually gradual

signs -
related to poor cardiac output - weakness, hypothermia, depression
congestion - pulmonary effusion, ascites, pleural effusion

4 types -
systolic myocardial - general reduction in ability of heart muscle
obstruction - external compression or something in vasculature
pressure overload - long term increases in stress to heart wall
volume overload - increased volume of blood in ventricles –> congestive heart failure

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13
Q

cardiac output

A

volume of blood expelled per unit time

affected by -
hypertension
valvular heart disease
cardiomyopathy
heart failure
pulmonary disease
arrhythmia
fluid overload
decreased fluid volume
electrolyte imbalance

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14
Q

cardiac index

A

cardiac output over body surface area

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15
Q

preload

A

degree of ventricular stretch when blood supplied to heart

increased by -
increased central venous pressure
increased expansion of ventricles
increased force of atrial contraction
increased aortic pressure
reduced heart rate
pathology - valve stenosis

decreased by -
decreased venous blood pressure
impaired atrial contraction
increased heart rate
decreased ventricular afterload
ventricular diastolic failure
inflow valve stenosis

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16
Q

afterload

A

load the heart must eject against

related to aortic pressure

increased by -
aortic valve stenosis
heart failure
increased systemic vascular resistance

decreased by -
medications to promote vasodilation
end stage shock

17
Q

tests for CVRS failure

A

blood pressure
radiography

lactate - lactate rises when anaerobic metabolism - sign of poor perfusion

acid base analysis - insufficient oxygen delivery from low blood oxygen (respiratory causes) or poor oxygen dlivery (cardiac causes) - more acidic

cardiac troponins - indicator of myocardial death (myocardial infarction)

NT-proBNP - differentiate between cardiac and respiratory causes of dyspnoea, released from cardiomyocytes when stretched

heartworm antigen - serology (antigen detectable 6 months after infection), modified knotts (performed at same time to catch false negatives)

18
Q

hypertrophic cardiomyopathy

A

most common heart disease in cats

thickened ventricular walls - left ventricle can’t fully relax and fill
areas of fibrosis
enlarged left ventricle
thrombosis
blood flow back into atrium

gross appearance -
pulmonary oedema
pleural effusion
enlarged heart - over 20kg
left ventricle and intraventricular septum thickened
dilated left atrium
thromboembolism in aortic trifurcation

histology - fibrosis

stain with massons trichrome to see myocytes (red) and fibrosis (blue)

different from restrictive cardiomyopathy - fibrosis on endocardial surface instead of myocytes

19
Q

Arrhythmogenic right ventricular cardiomyopathy

A

boxers

genetic - striatin production gene

syncope and sudden death with no previous signs noticed
arrhythmia

need section of right ventricle for pm diagnosis

20
Q

mitral valve disease

A

ckc spaniels

murmur
degeneration of fibrous layer of mitral valve
left sided heart failure

may see left atrium bulge in radiography

21
Q

endocarditis

A

microrganisms adhere to endocardium - proliferative lesions on valve surface
usually e coli, staph or strep - infection elsewhere, bacteria brought to heart in blood

endothelial death and thrombus formation

dirty IV catheter common cause in hospital

22
Q

pericardial effusions

A

pericardial sac fills with fluid

dogs - ruptured hemangiosarcoma
sheep - clostridium perfingens D

23
Q

Mulberry heart disease in pigs

A

vitamin E/selenium deficiency
ployphasic necrosis in heart and vasculature
mulberry look - multifocal red areas of myocardium

24
Q

foot and mouth in pigs

A

heart necrosis