Cushing syndrome - Primary Endocrine Tumors - Symptoms - Daignosis

Question 1

Adenomas Vs Carcinomas - 3

Answer 1

Adenomas are smaller
Carcinomas have no capsule
If secreting both will cause atrophy to the rest of the cortex (Cortizol or Aldosteron)

Question 2

Cushing syndrome - Symptoms - 8

Answer 2

1. Fat - Buffalo hump, Moon face, belly fat.
2. Proximal muscle weakness
3. Hyperglycemia, Polydipsia, Glucosuria.
4. Catabollic effects
5. More infections
6. Mental diseases
7. Period distribution
8. Hair ocer growth.

Question 3

Cushing syndrome - Diagnosis - 3

Answer 3

1. collect urine for 24 h to measure cortizol
2. measure ACTH
3. Dexmatzon depression test (If ACTH high and can be depressed its cusing disease, if cant be its ectopic secretion, if ACTH low its adrenal tumor.)