1
Q
Cells - 2
A
Chromafin
Sustentacular cells - support
2
Q
Tumors - 2
A
Pheochromocytoma - adults
Neuroblastoma - children
3
Q
Pheochromocytoma - law of 10 - 4
A
10% - outside of adrenal
10% - dual sided
10% - no elevation in BP.
10% - cancerous
4
Q
6 Familial mutations causing 25% of Pheochromocytoma
A
RET NF1 VHL SDHD SDHC SDHB last 4 activite HIF-1a. VHL also RCC.
5
Q
Pheochromocytoma - morphology
A
Alot of blood vessels, can be SALT AND PEPPER
6
Q
Pheochromocytoma - symptoms -
A
elevated BP - 90%
papitation attacks- 67%
7
Q
Pheochromocytoma - we look at urine for… - 2
A
Vanillylmandelic acid
Metanephrines
Adrenal Pathology
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