Adrenocortical neoplasms Flashcards
most neoplasms in adults are …
adenomas and carcinoma equally
most neoplasms in children are …
carcinoma
Most cases of neoplasm are…
sporadic
Familial genetic syndromes associated with adrenal neoplasm - 2
- LI fraumeni - P53 mutation.
2. Wiedemann-Beckwith
Most neoplasms secrete?
nop
Those who secrete Aldosterone or Cortizol are usually?
Adenomas
Those who secrete Androgens are usually?
Carcinoma
Adenocortical adenoma
Atypical cells, no necrosis. no mytosis
Adenocortical carcinoma
rare, can appear in children, can secrete Androgens, less causes HyperAdrenalisem. 2yr survival. can spread locally and hemtogenically.
Adenocortical carcinoma - Morphology
can be well or poor differentiated, giant cell are visible
Adrenal myelolypoma
Bone marrow in adrenal, its crazy. but usually meaningless
Incidentaloma
A non secretory adenoma. meaningless