CT Module 8 Flashcards
HOUNDSFIELD UNIT
A CT number that represents the attenuating properties or density of each tissue.
- Water is the reference tissue which is given a value of zero
- Tissue it’s the highest value will be white
- Tissue lower than the range will be black
WINDOW LEVEL
The CT # of the tissue of interest. Which CT # are displayed on the image
WINDOW WIDTH
It determines the gray levels to be displayed in the image.
This can be decreased or increased to produce an image
INCREASE WINDOW WIDTH
Wider range of values will be included into the grayscale,
- the image will have lower contrast
DECREASE WINDOW WIDTH
Less range of values included ,
- Image will have higher contrast
WIDE WINDOW WIDTH
More shades of gray with in the lung tissue
- Longer gray scale
Eg- Lung window WW: 1000, WL:-700
NARROW WINDOW WIDTH
Fewer shades of gray resulting into higher contrast image
Eg. Mediastinal window, soft tissue window. WW: 529, WL : 24
Lungs are completely black
PATIENT PREPARATION IN CT
- Verify patient -
- Briefly explain the procedure
- Obtain written consent for invasive procedures
- Describe to the patient how they will be positioned and table movement
- Provide time frame of procedure
- Explain what is expected of the patient for the procedure- breathing , no movement etc
- Describe the type of contrast to be used and it’s purpose
- Check for allergies if contrast is required
- Provide lead protection where appropriate
- Provide post procedural instructions
PUPOSE OF PATIENT HISTORY SHEET
- Patient safety- For contraindications
- Protocol Selection
- Clinical information - Help radiologist with diagnosis
-
BUN ( blood Urea nitrogen ) and Serum Creatinine
Used to measure patient kidney function
GFR ( glomerular filtration rate)
Normal values
120 ml/ min
Contrast will be given for a GFR greater than 30 ml/min
BUN ( blood urea nitrogen)
Normal values
7-21 mg/dl
SERUM CREATININE
NORMAL LEVEL
Male: 60-120 umol/L
Females: -100 umol/L
BLOODWORK
For Biopsy or drainage patients on warfarin
Prothrombin Time PT, Partial thromboplastin Time PTT and Platelet count will be viewed due to the increased risk of bleeding .
- patients on warfarin , heparin , plavix or aspirin may be instructed to discontinue before the procedure due increased risk of bleeding
aPURPOSE OF CONTRAST MEDIA IN CT
To distinguish adjacent structures on a CT image, creating a difference in attenuation values
- Used in CT to distinguish normal anatomy from pathology and to make various disease processes more visible
POSITIVE CONTRAST MEDIA
- Absorbs more radiation than the surrounding tissues therefore appears white or light on images
- Has high atomic number
- Positive Hounsfeild unit
- Radiopaque
- Eg Barium #56, Iodine # 53
NEGATIVE CONTRAST MEDIA
- Penetrated by X-rays more than surrounding tissues therefore appears black on images
- Low atomic number
- Radiolucent
- Negative Hounsfeild unit
- Eg, Air , CO2 and water
aGASTROINTESTINAL POSITIVE CONTRAST MEDIA IN CT
Barium Sulphate is used
- Introduce orally
- Used to distinguish the stomach, small intestine and large bowel from the surrounding soft tissue organs
- Only 1-3 % barium suspension is needed in CT due to its greater contrast resolution
- Patient drinks 450 ml of barium1-2 hours of scan and an addition of 100-200 ml is given just before the scan to fill the oesophagus, stomach and small bowel
- Contra indication- PERFORATION suspicion - this may cause peritonitis
aGASTROINTESTINAL POSITIVE CONTRAST MEDIA IN CT
WATER SOLUBLE CONTRAST MEDIA ( Gastrografin )
- Indicated for Abdo and pelvis scans when a perforation is suspected
- Has a bitter taste, often mixed with juice for palatability
- 2-5 % solutions is utilised in CT
- Patient drinks 300 ml of water mixed with 25ml of gastrografin
- Gatrografin is hypertonic thus May causes dehydration
- very dangerous when administered to elderly, infants or patients that are dehydrated,
GASTROINTESTINAL NEGATIVE CONTRAST MEDIA IN CT
WATER
- Negative contrast media/ enthral neutral
-Causes equal distension in the bowel as barium sulfate
- Use in clinical practice is increasing
GASTROINTESTINAL NEGATIVE CONTRAST MEDIA IN CT
CO 2
- Radiolucent contrast appears black on images
- Indicated for virtual colonoscopy exams
- Rectally administered
- Small flexible rectal tube is inserted and CO2 is administered via an automated insufflation system
- CO2 will distend the colon to better visualise polyps
- CO2 is absorbed in the body and excreted via the lungs
IV CONTRAST MEDIA
- Iodinated water soluble injectable contrast media eg omnipaque/ visipaque
- Indications to identify tumours, vascular structures, vascular pathology, renal function
- Two tissues must differ by at least 10 HU to be visibly different on CT scan
- Administration of contrast media May increase the attenuation difference between adjacent structures by 40-75 HU
CT MEDICAL HISTORY
Ask for the following
- Allergies history
- Chronic diseases
- Diabetes
- Renal dysfunctions
- Congestive heart failure
- patient older than 60
If yes to the above questions, patient must have a recent blood test to check Serum Creatinine levels
CONTRASTED CT
FOR PATIENTS TAKING METFORMIN
Contrast can be administered
- if eGFR is below 30mil/ min and contrast was administered, METFORMIN May be withheld 48hrs after the injection
- If renal dysfunction occurs post contrast METFORMIN could accumulate in the bloodstream and cause lactic acidosis
PROPERTIES OF IODINATED CONTRAST MEDIA
OSMOLARITY
The number of particles in solution, unit of liquid as compared to blood
- Blood osmolarity is 290mOsm/kgwater
PROPERTIES OF IODINATED CONTRAST MEDIA
HIGH OSMOLARITY CONTRAST MEDIA
Renografin. Hypaque
- Solution has 7-8 times the OSMOLARITY of plasma
PROPERTIES OF IODINATED CONTRAST MEDIA
LOW OSMOLARITY CONTRAST MEDIA
Omnipaque. Isovue
- Solution that has 2-3 times the osmolarity of plasma
PROPERTIES OF IODINATED CONTRAST MEDIA
ISO- OSMOLARITY
Solution that has equal osmolarity to plasma
Eg. Visipaque
PROPERTIES OF IODINATED CONTRAST MEDIA
aVISCOSITY
Thickness of fluid as it flows
- Viscosity of contrast media affects its injectability
- Contrast agents can be placed in a warmer to reduce its viscosity making it easier to inject
- The lose the concentration of iodine atoms within the contrast medium the less viscous the solution
PROPERTIES OF IODINATED CONTRAST MEDIA
IONICITY
- Ionic contrast media will dissociate into 2 charged particles when brought into solution
- Non ionic contrast media will not dissociate into 2 charged particles when brought into solution. THESE CONTRAST MEDIUMS USUALLY RESULT IN LOWER ADVERSE REACTIONS
- CONTRAST TODAY IS MOSTLY NON IONIC LOW OSMOLAR, DECREASING ADVERSE EFFECTS, SINCE THEY DONOT INDUCE FLUID IMBALANCE
PROPERTIES OF IODINATED CONTRAST MEDIA
CLEARANCE
- Iodinated contrast media is not metabolised, it is excreted by the kidneys via glomerularfiltration
- Half life in patients with normal renal function is 2 hours, and cleared 100% in 24 hrs
PROPERTIES OF IODINATED CONTRAST MEDIA
DOSE
- Determined by iodine concentration and volume of solution
- Contrast Media is measured in milligrams of iodine per lililiter
PROPERTIES OF IODINATED CONTRAST MEDIA
PEDIATRIC DOSE
- asked on weight
- Common formulae is 2ml per kg
BREASTFEEDING
CONTRAST
Less than 1% of contrast media given to mom will be excepted into the breast milk and absorbed by the infant
- THerefore it is SAFE to breastfeed after receiving iodinated contrast media
VASCULAR ACCESS IN CT
peripheral catheter
- 18-20 gauge Cather preferred
- Antecubital vein is the preferred site
- Patency must be confirmed with saline injection prior to hooking up IV line to the injector
VASCULAR ACCESS IN CT
PICC LINE
- Must be a purple PICC line to with stand the injector pressure
- Must flush with saline after injection
- Inserted in the cephalic or basilic vein and advanced to the SVC
- Can remain in place for weeks or months
INJECTOR PARAMETERS
- Volume and concentration of contrast
- Flow rate
- Pressure limit
- Timing between start of injection and start of scan
CT ARTERIAL PHASE
- Arterial structures are filled with contrast
- Begins immediately after injection
- AVID ( arteriovenous iodine difference) greater than 30 HU
- Application CT Angiography
NONEQUILIBRIUM ( Venous) Phase
- Venous and arterial structures are filled with contrast
- Begin around 60-70 sec post start of injection
- AVID ( arterial venous iodine difference) 10-30 H
- Application: Routine body scanning Eg appendix
EQUILIBRIUM ( Delayed ) PHASE
- Organ parenchyma opacified with contrast
- Begins around 2 min post start of injection
- AVID ( arterial venous iodine difference) less than 10 HU
- Application : kidneys
CONTRAST ENHANCEMENT FACTORS
- Injection parameters
- Condition of patient, particularly the patients cardiac output
NB: Injection protocols are designed by first determining the time during when the contrast material is likely to first arrive in the organ or vessel of interest
AUTOMATIC INJECTION TRIGGERING
Two methods
- test bolus
- Bolus triggering or tracing
TEST BOLUS
- Obtain scout image
- Determine target region, and obtain single slice
- Begin trail scans 8-15 secs after start of injection, scan every 2 sec using low. Ma
- 10-20ml of CM is injected and several trial scans are taken to determine the length of time from injection to peak contrast enhancement in the target region
- ROI on vessel
- Determine scan delay, peak enhancement via graph
- Trial scan delay + 2 x image @ peak enhancement +3 sec
BOLUS TRIGGERING
- Uses the contrast bolus itself to initiate the scan
- Obtain scout image
- Obtain single slice target region. ROI vessel
- Set trigger thresh hold or watch the graph to begin scan protocol
- Start the contrast injection, start the low radiation scans 8-10 sec later
- When the threshold is reached, start scan, the table will move to the start position and scanning begins
NB- A drawback is that a technologist cannot stay with the patient to monitor the injection site
SIDE EFFECTS OF CONTRAST MEDIA ADMINISTRATION
Common and predictable=
- Nausea
- Vomitting
- Metallic taste in the mouth
- Feeling warmth all over
- Feeling like you have peed your self ( especially4-5 sec post injection )
IDIOSYNCRATIC REACTIONS TO CONTRAST MEDIA ADMINISTRATION
These are not predictable, they are allergy like.
- They present quickly, usually within the first 5-20 min,
- High risk patients should be monitored for 1 hour after administration
- Not related to dose, can occur in small amounts being injected
CONTRAST MEDIA
RISK FACTORS
- Patients with multiple allergies to foods and or drugs
- Patients with asthma
- Patients who exhibited a reaction to previous contrast administration
CONTRAST MEDIA
PRE TREATMENT
- Un contrasted Ct must be down if possible for high risk iodine reaction patients if possible
- Pre treatment with Costicosteroids ( prednisone) and or Antihistamine diphenhydramine ( Benadryl) If CT with contrast is deemed necessary
MILD IDIOSYNCRATIC REACTIONS TO CONTRAST MEDIA
patient will begin to=
- Cough
- Sneeze
- Nasal congestion
- Exhibit a rash
- Itching
- Urticaria ( Hives)
Treatment =. Benadryl ( Diphenhydramine)
MODERATE TO SEVERE IDIOSYNCRATIC REACTIONS TO
CONTRAST MEDIA
- Dyspnea
- Wheezing
- Laryngeal Edema
- Hypertension or hypotension
Treatment =
- Oxygen for the Dyspnea
- Epinephrine for laryngeal Edema
CONTRAST INDUCED NEPHROPATHY. ( CIN)
Acute renal dysfunction that occurs after contrast media administration
NB: renal impairment is identified, continuance of the examination should be discussed with the radiologist
RISK FACTORS FOR CONTRAST INDUCED NEPHROPATHY. ( CIN)
- Pre-existing Azotemia
- Diabetic patients
- Multiple myeloma patients
- Patients over 60
- Administration of more than 200 ml of contrast media in one day
- Dehydrated patients
- Concurrent use of nephrotoxic drugs
AZOTEMIA
A medical condition in which patient has elevated levels of urea, creatinine, relating to inadequate filtering of blood by kidney