CSIM 1.23 - Sexually Transmitted Diseases

Question 1

What is the most common STI in the UK and how is this transmitted?

Answer 1

Chlamydia Trachomatis

Sexual contact and vertical transmission

Question 2

Which serotypes of chlamydia trachomatis cause eye infections (trachoma)?

Answer 2

Chlamydia A
Chlamydia B
Chlamydia C

Question 3

Which serotypes of chlamydia trachomatis cause genital infections?

Answer 3

D - K

Question 4

Name four common symptoms associated with genital chlamydia?

Answer 4

Non-gonoccocal urethritis (mucoid discharge)
Cervicits
Vaginal discharge
Endometritis and Epididymitis - recurrent infections lead to infertility

Question 5

What is the treatment used for chlamydia trachomatis infections?

Answer 5

Azithromycin

beta lactems do NOT work

Question 6

Describe niesseria gonorrhoea?

Answer 6

Gram negative (-) 
Anaerobic diplococci

Question 7

What are the clinical manifestations of niesseria gonorrhoea?

Answer 7

50% women and 5% men are asymptomatic

Symptoms = opthalmia neonatorum (neonatal conjunctivitis)//urethritis//dysuria

Question 8

What is treponema pallidium also known as?

Answer 8

Syphilis

Question 9

Describe the three progressive stages of syphilis?

Answer 9

Primary syphilis = lesion (chacre) forms at site which heals without treatment needed - organism spreads through the lymphatics
Secondary syphilis = Red maculopapular rash and condylomata lata - 80% of people enter latency
Tertiary syphilis = dementia and gumata

Question 10

Describe papilloma virus and its clinical manifestations?

Answer 10

Double stranded DNA
Non enveloped
Causes hyperplastic epithelial lesions - can lead to cervical cancer!

Question 11

Which papilloma virus infect the anogenital tract?

Answer 11

HPV 6
HPV 11
HPV 16
HPV 18

Question 12

Which papilloma virus cause planter and facial warts?

Answer 12

HPV 1

HPV 4