Creutzfeld-Jakob Disease Flashcards
1
Q
What is CJD?
A
Rapidly progressive neurological condition caused by prion proteins
2
Q
What are features of CJD?
A
Rapid onset dementia
Myoclonus
3
Q
How is suspected CJD investigated?
A
LP - usually normal
EEG
MRI - hyperintense signals in basal ganglia + thalamus
4
Q
What are the types of CJD?
A
Sporadic
New variant
5
Q
What is sporadic CJD?
A
Spontaneously occurring CJD
Mean age of onset = 65
6
Q
What is new variant CJD?
A
Younger onset
Psychological symptoms
- anxiety
- dysphonia
Protein on chromosome 20
7
Q
How is CJD managed?
A
Supportive care
