Cranial/Spinal Dyfunction - Willard Flashcards
Which system takes little energy to activate, is highly myelinated, uses Aa & AB fibers and is responsible for discriminatory touch sensation?
Large fiber system
Which system takes more energy to activate, is lowly myelinated, uses AD & C fibers and is responsible for pain sensation?
Small fiber system
What are PAN endings?
Primary afferent nocicepter endings
Naked nerve ending exposed to intracellular environment that help detect pain
Part of small fiber system
What is the neurogenic inflammatory cycle?
Tissue inflammation → release of histamine, bradykinin & PGs → activation/senstitization of PANs → more output to spinal cord
FEED FORWARD EVENT
What does the gate-controlled theory of inhibition state?
Large fiber going up the thalamus synapses on an inhibitory interneuron which can shut off the pathway up to the thalamus
What does the locus coeruleus produce?
Norepinephrine → increases sympathetic nervous system
What does the hypothalamus produce?
Cortisol → increases adrenal steroid system
What is involved in negative feedback of the arousal system by being sensitive to cortisol and inhibiting the arousal system?
Hippocampus
What is involved in positive feedback of the arousal system?
Amygdala
