Audition - Martin Flashcards
Impendance matching
Improve hearing by focusing signals into a small space (TM)
In which direction does the pinna help localize sound?
Vertically
Inner hair cells
Secrete neurotransmitter onto AFFERENT nerve fibers
Outer hair cells
- Have mostly EFFERENT fibers
- Amplify the signal by adjusting the difference between the two membranes, allowing greater inner hair cell response
Signal transduction
Influx of K+ depolarizes the hair cell leading to:
- Voltage-gated Ca2+ channels open
- Influx of Ca2+ causes transmitter release
- Transmitter depolarizes nerve fiber inducing action potential that travels to the brain
Fourier analysis
Cochlea breaks complex tones down into component sinusoidal waves
Tuning curve
Curve that describes the frequency of the sound that the cell will respond to at different loudness levels (the further cells are apart the greater the difference in tone frequency that they will respond to)
Place coding
The brain interprets incoming signals carried by a particular nerve fiber in reference to its specific place on the cochlea
Volley coding
A small group of CN VIII axons carry action potentials from the Organ of Corti
Central processing
Some inferior colliculus neurons respond to frequency modulated sound while others respond to duration
Thalamic processing
Medial geniculate preserve tonotopy
Tonotopical organization
Inner hair cells in cochlea that are adjacent to each other have almost the same frequency response properties
Types of peripheral acquired hearing loss
Conduction: b/c of wax blockage or ossicle damage
Sensorineural: death of cells in CN VIII or hair cell damage
Presbycusis: B/L hearing loss w/age
Cochlear implants
Electrode array is inserted through round window, a speech analyzer breaks down sounds into component tones and stimulates the electrode array to deliver depolarizing pulses at those spots where the cochlea would normally respond to those tones
Penetrating auditory brainstem implants (PABI)
Used when CN VIII fibers in the organ of corgi are missing or non-functional