Cranial Nerves Flashcards
What does the brainstem adjoin?
The brain and the spinal cord
What are the parts of the brainstem?
- Pons
- Medulla
- Mid-brain
Is the medulla functionally that different from the spinal cord?
Yes, very different
What is the brainstem continuous with caudally?
The spinal cord
Where does the brainstem have a vital role?
In regulation of cardio-respiratory functions and maintaining consciousness
What runs through brainstem?
Ascending and descending fibres between the brain and the rest of the body run through it
What is the brainstem the location of?
The majority of cranial nerve nuclei
What are nuclei, in terms of the cranial nerves?
Collections of cell bodies of nerve fibres that make up the whole cranial nerve
What are the cranial nerves part of?
The peripheral nervous system
Where do the cranial nerves arise from?
The central nervous system, at the level of the brainstem, or forebrain in the case of olfactory or optic nerve
How many pairs of cranial nerves are there?
12
What does each cranial nerve do?
Innervates halves, as they are in pairs
Describe the intervals that the cranial nerves arise from the brainstem (or brain)
Irregular intervals from CNS, rather than segments as seen in spinal nerves
What does each cranial nerve have for identification?
A roman numeral
What does the numberous of the cranial nerve generally follow?
The order in which they arise (or enter) the brainstem, from rostal to caudal
What do cranial nerves carry?
1000’s of axons
What are the potential types of axons in cranial nerves?
- General sensory
- Special sensory
- Motor
- Autonomic
How many of the cranial nerves are mixed?
Only four
What is meant by a mixed cranial nerve?
Contain both motor and sensory modalities
What is the special sense taste carried within?
Two of the mixed cranial nerves, mainly CN VII and CN IX
How many of the cranial nerves are purely sensory?
3
What do the sensory cranial nerves do?
Carry special sensory function, as opposed to general sensation
What cranial nerve is responsible for hearing and balance?
CN VIII
What cranial nerve is responsible for vision?
CN II
What cranial nerve is responsible for smell?
CN I
How many of the cranial nerves are purely motor?
5
How many of the cranial nerves carry efferent autonomic fibres?
4
Which cranial nerves carry efferent autonomic fibres?
CN III, CN VII, CN IX, and CN X
What are the cranial nerves that carry efferent autonomic fibres known as?
Visceral motor
What cranial nerve is the most rostal?
Olfactory
What is CN I?
Olfactory
What route does CN I take?
Long nerves dangle down through the cribiform plate, into the olfactory mucosa of the roof of the nasal cavity
What is the sensory function of CN I?
Smell
Is CN I motor or sensory?
Sensory
How is CN I tested?
- Test one nostril at time
- Smelling salts, or something quite odouress
Is CN I often formally tested?
No, just ask if they have noticed any change/loss in sense of smell
Is CN I a true cranial nerve?
No, they are paired extensions of the forebrain
What is the clinical term for loss of smell?
Ansomnia
What is the most common cause of ansomnia?
Upper respiratory tract infection
How can a head injury cause ansomnia?
A bump to the head can cause the brain to wobble, which can produce shearing forces or a basilar skull fracture
What is CN II?
Optic nerve
What route does CN II take?
Comes from retina, through optic canal. Cross over at the optic chiasms, to optic tracts, to forebrain
Is CN II motor or sensory?
Sensory
What is the sensory function of CN II?
Vision
How is CN II tested?
- Test one eye at a time
- Visual tests; visual acuity and visual fields
- Test pupils
Is CN II a ‘true’ cranial nerve?
No, paired anterior extensions of the forebrain
How can CN II be seen directly?
With fundoscopy
What is the result of the complex pathway from the retina to the visual cortex of the occipital lobe?
Different lesions give very different patterns of visual loss
What can cause lesions of CN II?
- Optic neuritis
- Pituitary tumour
- Stroke
What is optic neuritis?
Inflammation of optic nerve
What can happen, regarding CN II, when there is a pituitary tumour?
Tumours can squash the chiasm, and because of intermingling here, can cause bilateral visual deficit
What is CN III?
Oculomotor nerve
What route does CN III take?
Passes grom midbrain to the orbit through the superior orbital fissure. Runs through the cavernous sinus
Is CN III motor or sensory?
Motor
What is the motor function of CN III?
- Ciliary muscles
- Sphincter of pupil
- All extrinsic muscles of the eye, except those supplied by CN IV and VI
How is CN III tested?
- Inspection of the eyelids and pupils
- Eye movements
- Pupillary light reflexes
How will a damaged CN III present?
Double vision (diplopia), with eye in down and out position, severe ptosis, and maybe pupillary dilation
What can cause CN III lesions?
- Raised intracranial pressure (tumour or haemorrhage)
- Aneurysms of the posterior communicating artery
- Cavernous sinus thrombosis from infection or clot
- Diabetes/hypertension
What is the first sign of raised intracranial pressure?
Blown pupil
Why does a blown pupil signify raised intracranial pressure?
Superficial parasympathetics run with the oculomotor nerve on the outside, so if pressure exerted from the outside, it affects parasympathetics first. This leads to a loss of sphincter control, and therefore a blown pupil
What CN III lesion will not cause a blown pupil?
Diabetes/hypertension