Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

BPM1 Exam 4 - Cardiovascular, Pulmonary, and Renal 1 > CPR 14 - Reactive Oxygen Species > Flashcards

CPR 14 - Reactive Oxygen Species Flashcards

1
Q

List the common free radical and compounds that lead to free radical formation.

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is ROS formation enhanced by?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Describe how superoxide is formed and where in the cell it is formed.

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Describe what compound forms superoxide in the ETC.

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What scavanges superoxide? How? Where? What cofactors do they use?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the most dangerous ROS?

A

Hydroxyl radical OH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Describe the ways that hydroxyl radical OH is formed.

A

It can also be formed from water with ionizing radiation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What scavenges H2O2?

A

Catalase or glutathione peroxidase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Where is catalase found and how does it break down H2O2?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is GSH?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What does glutathione peroxidase act on besides H2O2? How does it reduce these oxides?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How can PUFAs become oxidized? How is this fixed and what can happen if it isn’t fixed?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What type of nucleic acid polymer is more susceptible to ROS damage and why?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What type of physical injury (not radiation) can lead to radical formation and how?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

List the nonenzymatic radical scavengers.

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

List the dietary radical scavengers and the types of foods they’re found in.

A
17
Q

What does a SOD deficiency lead to? What causes this deficiency?

A
18
Q

Describe what ALS is, what its symptoms are, and when it usually occurs in life.

A
19
Q

Aside from within a peroxisome, why would a cell want to create ROSs and RNOSs? Which cells do this?

A
20
Q

How do phagocytic cells make ROSs and RNOSs?

A
21
Q

What is a respiratory burst?

A

When a neutrophil engulfes a pathogen it uses a large amount of oxygen to form superoxides used to kill the pathogen. This comsumption of oxygen is referred to as a respiratory burst.

22
Q

Where NADPH oxidase found in neutrophils?

A

Cell membrane

23
Q

Hypochlorous acid is most effective against which type of pathogens? What is another name for hypochlorous acid?

A

Bacteria and fungi

bleach

24
Q

What is the vesicle called that phagocytic cells use to store radicals for killing pathogens?

A

Phagolysosome

25
Q

Where are MPOs (myeloperoxidases) found in phagocytic cells? Why?

A
26
Q

What gives pus its color?

A

The heme like groups that MPO uses

27
Q

What are the major physiological funcions of nitric oxide?

A
28
Q

How is NO related to sepsis?

A
29
Q

What is chronic granulomatous disease? What are its symptoms, age of onset, and inheritance pattern?

A
30
Q

What is candida albicans?

A
31
Q

True or False - recurrent severe infections occur with candida albicans because bacteria is no longer destroyed.

A

BPM1 Exam 4 - Cardiovascular, Pulmonary, and Renal 1 (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions