CPOP Flashcards
What is some examples of the substance dependence criteria?
> … how to explain how addicted someone is to substance use
- Tolerance •
- \Withdrawal •
- Compulsion to use •
- Difficulties controlling use •
- Priority of use over other activities •
- Continued use despite harmful consequences
What are examples of drug related harm?
- Illness and disease –> Hep C and HIV
- Accidents and injury
- Family and social disruption
- Crime and violence
- Workplace and economic costs
What is used for opioid substitution treatment (OST)? Why is it used? Benefits?
Methadone and buprenorphine
- OST replaces short-acting opioids, such as heroin or oxycodone, with a long-acting opioid that can be taken orally
- OST is designed to have a minimal intoxicating effect, blocking the euphoria associated with use of exogenous opioids and preventing withdrawal
What are the factors involving drug use?
- Drug
- Individual
- Environment
Who is Community Program for Opioid Pharmacotherapy (CPOP) co-managed by?
Co-managed by the Medicines and Poisons Regulatory Branch and Next Step Drug & Alcohol Services to enable the provision of methadone and buprenorphine
What are some role of community pharmacotherapy program (CPP)?
- Coordinates the Clinical Advisory Service
- Arranges interstate and international transfers for opioid pharmacotherapy clients coming to and leaving from WA
- Supports CPOP prescribers, pharmacists, and clients with access, prescribing and dispensing issues
- Supports prison release arrangements for continuing pharmacotherapy treatment in the community
- Review all community applications for Community Program for Opioid Pharmacotherapy (CPOP) treatment and process to HDWA for authorisation
What is the clinical advisory service (CAS)? What can CAS doctors do?
Operates a 24/7 phone service for health professionals to access clinical advice on patient management involving alcohol and drug use issues with access to experienced medical practitioners through Next Step Drug & Alcohol Service
- CAS doctors can also provide interim CPOP prescriptions on behalf of all CPOP prescribers to ensure continuity of treatment. CPP coordinates the CAS during business hours
Medical practitioners authorised to prescribe methadone and/or buprenorphine in WA sign an agreement to comply as required by the ….
WA Schedule 8 Medicines Prescribing Code (2017)
What is the role of the clinical review committee (CRC)?
The CPOP Clinical Review Committee meets to review and endorse applications for OST that fall outside the WA Policies and Procedures, to review the management of clients with special dosing approval, and to respond to clinical management issues which may impact upon service providers and clients of the Program
What is the CPOP committee structure?
What are the two training options to become a CPOP prescriber?
- CPOP Prescriber Training enables prescribing of methadone and buprenorphine for up to 50 patients (25 for solo rural practitioners)
- Buprenorphine Prescriber Online Training enables prescribing of buprenorphine products for up to 5 patients.
> Every three years prescribers are required to complete a Reaccreditation Assessment and provide feedback on their level of confidence in areas related to CPOP treatment to continue their authorisation
Pharmacies dispensing and supervising methadone and buprenorphine treatment for opioid dependence must be authorised by the …
Department of Health
Prescribers submit an Application to Prescribe Opioid Substitution Treatment detailing: (10 steps)
- The type of application
- The patient (ID, demographics)
- Transfer (from other CPOP prescriber)
- Treatment (OST type, induction plan)
- Other treatment details (interacting meds)
- Pharmacy
- Drug use
- Patient acknowledgement (signed)
- Prescriber
- Prescriber declaration (signed)
Applications from community CPOP prescribers are reviewed by CPP for clinical issues prior to submissions to the Health Department
Patients considering CPOP Treatment must be fully aware that commencing pharmacotherapy treatment of opioid dependence results in their name being placed on the?
WA drugs of addiction record
> record restricts access to other S8 medicines
> information from the Record is only provided to health professionals who are involved in the patient’s treatment
What should the prescription of OST include?
What are some pharmacokinetics of methadone?
- Methadone is highly lipophilic and binds to a range of body tissues including the lungs, kidneys, liver and spleen such that the concentration of methadone in these organs is much higher than in blood
- Methadone is primarily broken down in the liver via the cytochrome P450 enzyme system
- Methadone is also secreted in sweat and saliva
What are some pharmacokinetics for buprenorphine?
- Peak plasma concentrations are achieved 1 to 2 hours after sublingual administration
- When given sublingually it bypasses the liver and is able to reach the bloodstream to have a therapeutic effect –> naloxone administered orally or sublingually has no detectable pharmacological activity
- By stimulating the mu (u) receptor only partially, buprenorphine creates those effects with less intensity than heroin, morphine, or methadone, all of which stimulate the receptor fully
- buprenorphine provides a positive but moderate psychoactive effect that reduces craving and blocks the effects of other opioids
- Buprenorphine displaces other agonists from opioid receptors, and may not produce sufficient agonist effects initially to compensate for the displaced methadone or heroin. The client may experience opioid withdrawal within 1-4 hours after first administration
When can takeaway doses be provided?
- takeaway doses should not be considered until the patient has been in six months of continuous treatment
- Limitations on takeaway doses ensure that treatment is not compromised if takeaways are lost or stolen and reduces the potential for misuse
NO MORE THAN 2 DOSES AT A TIME
What is the reintroduction schedule of missed doses?
