CP Theme 8

Question 1

Neoplasm where the proliferation of haematopoietic stem cells leads to scarring of the marrow?

Answer 1

Myelofibrosis

Question 2

Possible severe complication of intensive chemotherapy in acute leukaemia?

Answer 2

Neutropenic Sepsis

Question 3

Type of anaemia associated with folic acid deficiency?

Answer 3

Megaloblastic

Question 4

The most common heritable bleeding disorder?

Answer 4

Von Willebrand Disease

Question 5

Lineage associated with the production of erythrocytes?

Answer 5

Myeloid

Question 6

Widespread activation of the clotting cascade resulting in the formation of clots throughout the small blood vessels?

Answer 6

Disseminated Intravascular Coagulation

Question 7

Oral anticoagulant used to prevent thrombosis and thromboembolism?

Answer 7

Warfarin

Question 8

Increase in the number of red blood cells?

Answer 8

Polycythaemia

Question 9

X-linked recessive disorder resulting in factor VIII deficiency?

Answer 9

Haemophilia

Question 10

Malignant clonal proliferation of plasma cells?

Answer 10

Myeloma

Question 11

A laboratory technique where serum is placed on a gel and exposed to an electric current?

Answer 11

Protein Electrophoresis

Question 12

Tyrosine kinase inhibitor that is effective in CML?

Answer 12

Imatinib

Question 13

The physiological developmental process that gives rise to the cellular components of blood?

Answer 13

Haemopoiesis

Question 14

Type of anaemia commonly resulting in a microcytic hypo chromic picture?

Answer 14

Iron Deficiency

Question 15

A possible treatment for younger patients particularly with acute leukaemia?

Answer 15

Bone Marrow Transplant

Question 16

Type of anaemia associated with atrophic gastritis?

Answer 16

Pernicious

Question 17

The process of mixing a patients plasma with aliquots of donor red cells to see if a reaction occurs?

Answer 17

Crossmatching

Question 18

Neoplastic disorder of lymphoid tissue usually associated with t(14;18)?

Answer 18

Follicular Lymphoma

Question 19

Granulocytes that are often increased in parasitic infections and allergies?

Answer 19

Eosinophils

Question 20

Autosomal recessive disorder leading to defective alpha or beta global chains?

Answer 20

Thslassaemia

Question 21

Small red spots (

Answer 21

Petechiae

Question 22

Chromosomal abnormality seen in CML?

Answer 22

Philadelphia Chromosome

Question 23

Genetic blood disorder resulting in a rigid abnormally shaped red blood cell?

Answer 23

Sickle Cell Disorder

Question 24

Can be used to treat life-threatening bleeding in patients on warfarin?

Answer 24

Fresh Frozen Plasma

Question 25

Hormone that controls red blood cell production?

Answer 25

Erythropoietin

Question 26

Organ essential to the maintenance of normal levels of coagulation factors?

Answer 26

Liver