CP Theme 2 Flashcards

1
Q

Class of drug used to manage allergic rhinitis?

A

Antihistamine

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2
Q

Term used to describe the abnormally low levels of neutrophil polymorphs in the blood?

A

Neutropenia

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3
Q

Autoantibodies formed in systemic lupus erythematosus?

A

Anti-nuclear antibodies

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4
Q

Test that precedes the identification of suitable donor blood prior to transfusion?

A

Cross-matching

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5
Q

Autoimmune disease leading to ischaemia and fibrosis?

A

Scleroderma

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6
Q

Non-specific test for inflammation that involves the rate at which red blood cells sediment?

A

ERS

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7
Q

Secondary lymphoid organ?

A

Spleen

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8
Q

Acronym for a class of drug used to treat RA patients, which includes gold?

A

DMARD

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9
Q

A measure of how good a test is at identifying people with a disease?

A

Sensitivity

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10
Q

Thought to be a major trigger in atopic disease?

A

House dust mite

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11
Q

Type 1 hypersentitivity reaction

A

Anaphylactic

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12
Q

Autoimmune liver disease associated with anti-mitochondrial antibodies?

A

Primary biliary sclerosis

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13
Q

The act of manipulating the immune system to achieve a desired response?

A

Immunomodulation

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14
Q

X-linked condition associated with a lack of antibodies in the bloodstream?

A

Agammaglobulinaemia

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15
Q

Antibodies produced by an individual that cause agglutination of the red blood cells of others?

A

Isoagglutinins

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16
Q

Type of immunity facilitated by B lymphocytes?

A

Humoral

17
Q

Syndrome with defective B and T cells?

A

Severe combined immunodeficiency

18
Q

Anti-body-mediated rejection usually occurring hours-to-days after transplantation is known as?

A

Hyperacute

19
Q

Class of immunosuppressive drug with side effects including diabetes, poor wound healing and osteoporosis?

A

Corticosteroid

20
Q

An autoimmune disease that affects the joints?

A

RA

21
Q

An autoimmune disease that affects the thyroid?

A

Graves Disease

22
Q

Any event which stimulated an MHC-directed immune response?

A

Sensitisation

23
Q

Autoimmue granulomatous vasculitis in which ANCA are detected?

A

Wegeners Granulomatosis

24
Q

Locus if genes that encode for proteins on the surface of cells that irresponsible for regulating the human immune system?

A

Human leukocyte antigen

25
Q

Situation where the immune system is not effective enough to protect the body from infection?

A

Immunodeficiency

26
Q

Chimeric mouse-human monoclonal antibody used to treat autoimmune disease e.g. Crohn’s disease?

A

Infliximab

27
Q

Allergic disease associated with inflammation and hyperactivity of the small airways?

A

Asthma

28
Q

Acronym for a very specific antibody in rheumatoid arthritis?

A

ACPA